Transcription factor Sp3 (SPR-2)
1_MTAPE 6_ KPVKQ 11_ EEMAA 16_ LDVDS 21_ GGGGG 26_ GGGGH 31_ GEYLQ 36_ QQQQH 41_ GNGAV 46_ AAAAA 51_ AQDTQ 56_ PSPLA 61_ LLAAT 66_ CSKIG 71_ PPSPG 76_ DDEEE 81_ AAAAA 86_ GAPAA 91_ AGATG 96_ DLASA 101_ QLGGA 106_ PNRWE 111_ VLSAT 116_ PTTIK 121_ DEAGN 126_ LVQIP 131_ SAATS 136_ SGQYV 141_ LPLQN 146_ LQNQQ 151_ IFSVA 156_ PGSDS 161_ SNGTV 166_ SSVQY 171_ QVIPQ 176_ IQSAD 181_ GQQVQ 186_ IGFTG 191_ SSDNG 196_ GINQE 201_ SSQIQ 206_ IIPGS 211_ NQTLL 216_ ASGTP 221_ SANIQ 226_ NLIPQ 231_ TGQVQ 236_ VQGVA 241_ IGGSS 246_ FPGQT 251_ QVVAN 256_ VPLGL 261_ PGNIT 266_ FVPIN 271_ SVDLD 276_ SLGLS 281_ GSSQT 286_ MTAGI 291_ NADGH 296_ LINTG 301_ QAMDS 306_ SDNSE 311_ RTGER 316_ VSPDI 321_ NETNT 326_ DTDLF 331_ VPTSS 336_ SSQLP 341_ VTIDS 346_ TGILQ 351_ QNTNS 356_ LTTSS 361_ GQVHS 366_ SDLQG 371_ NYIQS 376_ PVSEE 381_ TQAQN 386_ IQVST 391_ AQPVV 396_ QHLQL 401_ QESQQ 406_ PTSQA 411_ QIVQG 416_ ITPQT 421_ IHGVQ 426_ ASGQN 431_ ISQQA 436_ LQNLQ 441_ LQLNP 446_ GTFLI 451_ QAQTV 456_ TPSGQ 461_ VTWQT 466_ FQVQG 471_ VQNLQ 476_ NLQIQ 481_ NTAAQ 486_ QITLT 491_ PVQTL 496_ TLGQV 501_ AAGGA 506_ FTSTP 511_ VSLST 516_ GQLPN 521_ LQTVT 526_ VNSID 531_ SAGIQ 536_ LHPGE 541_ NADSP 546_ ADIRI 551_ KEEEP 556_ DPEEW 561_ QLSGD 566_ STLNT 571_ NDLTH 576_ LRVQV 581_ VDEEG 586_ DQQHQ 591_ EGKRL 596_ RRVAC 601_ TCPNC 606_ KEGGG 611_ RGTNL 616_ GKKKQ 621_ HICHI 626_ PGCGK 631_ VYGKT 636_ SHLRA 641_ HLRWH 646_ SGERP 651_ FVCNW 656_ MYCGK 661_ RFTRS 666_ DELQR 671_ HRRTH 676_ TGEKK 681_ FVCPE 686_ CSKRF 691_ MRSDH 696_ LAKHI 701_ KTHQN 706_ KKGIH 711_ SSSTV 716_ LASVE 721_ AARDD 726_ TLITA 731_ GGTTL 736_ ILANI 741_ QQGSV 746_ SGIGT 751_ VNTSA 756_ TSNQD 761_ ILTNT 766_ EIPLQ 771_ LVTVS 776_GNETM
1: Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping