Otoconin-90 (Oc90) (Phospholipase A2 homolog)
1_MIAFL 6_ LTSVL 11_ MIPHA 16_ GGHPL 21_ DTPHL 26_ PQELP 31_ PGLPN 36_ NINIT 41_ FFSGM 46_ FKNVE 51_ SVAEI 56_ FDCLG 61_ PHFTW 66_ LQAVF 71_ TNFPV 76_ LIQFV 81_ NGMKC 86_ VAGLC 91_ PRDFE 96_ DYGCT 101_ CRFEM 106_ EGLPV 111_ DESDS 116_ CCFQH 121_ RRCYE 126_ EAAEM 131_ DCLQD 136_ PAKLS 141_ TEVNC 146_ VSKKI 151_ ICESK 156_ DNCEH 161_ LLCTC 166_ DKAAI 171_ ECLAR 176_ SSLNS 181_ SLNLL 186_ DTSFC 191_ LAQTP 196_ ETTIK 201_ EDLTT 206_ LLPRV 211_ VPVEP 216_ TDTSL 221_ TALSG 226_ EEAGH 231_ DQEGV 236_ GAARA 241_ TSPPG 246_ SAEIV 251_ ATRVT 256_ AKIVT 261_ LVPAG 266_ IKSLG 271_ LAVSS 276_ VENDP 281_ EETTE 286_ KACDR 291_ FTFLH 296_ LGSGD 301_ NMQVM 306_ PQLGE 311_ MLFCL 316_ TSRCP 321_ EEFES 326_ YGCYC 331_ GQEGR 336_ GEPRD 341_ DLDRC 346_ CLSHH 351_ CCLEQ 356_ VRRLG 361_ CLLER 366_ LPWSP 371_ VVCVD 376_ HTPKC 381_ GGQSL 386_ CEKLL 391_ CACDQ 396_ TAAEC 401_ MTSAS 406_ FNQSL 411_ KSPSR 416_ LGCPG 421_ QPAAC 426_ EDSLH 431_ PVPAA 436_ PTLGS 441_ SSEED 446_ SEEDP 451_ PQEDL 456_ GRAKR 461_ FLRKS 466_ LGPLG 471_IGPLH
1: Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OTOL1, modulates calcite crystal morphology and growth kinetics. It is unlikely that this protein has phospholipase A2 activity