DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme)
1_MAKSG 6_ GCGAG 11_ AGVGG 16_ GNGAL 21_ TWVTL 26_ FDQNN 31_ AAKKE 36_ ESETA 41_ NKNDS 46_ SKKLS 51_ VERVY 56_ QKKTQ 61_ LEHIL 66_ LRPDT 71_ YIGSV 76_ EPLTQ 81_ FMWVY 86_ DEDVG 91_ MNCRE 96_ VTFVP 101_ GLYKI 106_ FDEIL 111_ VNAAD 116_ NKQRD 121_ KNMTC 126_ IKVSI 131_ DPESN 136_ IISIW 141_ NNGKG 146_ IPVVE 151_ HKVEK 156_ VYVPA 161_ LIFGQ 166_ LLTSS 171_ NYDDD 176_ EKKVT 181_ GGRNG 186_ YGAKL 191_ CNIFS 196_ TKFTV 201_ ETACK 206_ EYKHS 211_ FKQTW 216_ MNNMM 221_ KTSEA 226_ KIKHF 231_ DGEDY 236_ TCITF 241_ QPDLS 246_ KFKME 251_ KLDKD 256_ IVALM 261_ TRRAY 266_ DLAGS 271_ CRGVK 276_ VMFNG 281_ KKLPV 286_ NGFRS 291_ YVDLY 296_ VKDKL 301_ DETGV 306_ ALKVI 311_ HELAN 316_ ERWDV 321_ CLTLS 326_ EKGFQ 331_ QISFV 336_ NSIAT 341_ TKGGR 346_ HVDYV 351_ VDQVV 356_ GKLIE 361_ VVKKK 366_ NKAGV 371_ SVKPF 376_ QVKNH 381_ IWVFI 386_ NCLIE 391_ NPTFD 396_ SQTKE 401_ NMTLQ 406_ PKSFG 411_ SKCQL 416_ SEKFF 421_ KAASN 426_ CGIVE 431_ SILNW 436_ VKFKA 441_ QTQLN 446_ KKCSS 451_ VKYSK 456_ IKGIP 461_ KLDDA 466_ NDAGG 471_ KHSLE 476_ CTLIL 481_ TEGDS 486_ AKSLA 491_ VSGLG 496_ VIGRD 501_ RYGVF 506_ PLRGK 511_ ILNVR 516_ EASHK 521_ QIMEN 526_ AEINN 531_ IIKIV 536_ GLQYK 541_ KSYDD 546_ AESLK 551_ TLRYG 556_ KIMIM 561_ TDQDQ 566_ DGSHI 571_ KGLLI 576_ NFIHH 581_ NWPSL 586_ LKHGF 591_ LEEFI 596_ TPIVK 601_ ASKNK 606_ QELSF 611_ YSIPE 616_ FDEWK 621_ KHIEN 626_ QKAWK 631_ IKYYK 636_ GLGTS 641_ TAKEA 646_ KEYFA 651_ DMERH 656_ RILFR 661_ YAGPE 666_ DDAAI 671_ TLAFS 676_ KKKID 681_ DRKEW 686_ LTNFM 691_ EDRRQ 696_ RRLHG 701_ LPEQF 706_ LYGTA 711_ TKHLT 716_ YNDFI 721_ NKELI 726_ LFSNS 731_ DNERS 736_ IPSLV 741_ DGFKP 746_ GQRKV 751_ LFTCF 756_ KRNDK 761_ REVKV 766_ AQLAG 771_ SVAEM 776_ SAYHH 781_ GEQAL 786_ MMTIV 791_ NLAQN 796_ FVGSN 801_ NINLL 806_ QPIGQ 811_ FGTRL 816_ HGGKD 821_ AASPR 826_ YIFTM 831_ LSTLA 836_ RLLFP 841_ AVDDN 846_ LLKFL 851_ YDDNQ 856_ RVEPE 861_ WYIPI 866_ IPMVL 871_ INGAE 876_ GIGTG 881_ WACKL 886_ PNYDA 891_ REIVN 896_ NVRRM 901_ LDGLD 906_ PHPML 911_ PNYKN 916_ FKGTI 921_ QELGQ 926_ NQYAV 931_ SGEIF 936_ VVDRN 941_ TVEIT 946_ ELPVR 951_ TWTQV 956_ YKEQV 961_ LEPML 966_ NGTDK 971_ TPALI 976_ SDYKE 981_ YHTDT 986_ TVKFV 991_ VKMTE 996_ EKLAQ 1001_ AEAAG 1006_ LHKVF 1011_ KLQTT 1016_ LTCNS 1021_ MVLFD 1026_ HMGCL 1031_ KKYET 1036_ VQDIL 1041_ KEFFD 1046_ LRLSY 1051_ YGLRK 1056_ EWLVG 1061_ MLGAE 1066_ STKLN 1071_ NQARF 1076_ ILEKI 1081_ QGKIT 1086_ IENRS 1091_ KKDLI 1096_ QMLVQ 1101_ RGYES 1106_ DPVKA 1111_ WKEAQ 1116_ EKAAE 1121_ EDETQ 1126_ NQHDD 1131_ SSSDS 1136_ GTPSG 1141_ PDFNY 1146_ ILNMS 1151_ LWSLT 1156_ KEKVE 1161_ ELIKQ 1166_ RDAKG 1171_ REVND 1176_ LKRKS 1181_ PSDLW 1186_ KEDLA 1191_ AFVEE 1196_ LDKVE 1201_ SQERE 1206_ DVLAG 1211_ MSGKA 1216_ IKGKV 1221_ GKPKV 1226_ KKLQL 1231_ EETMP 1236_ SPYGR 1241_ RIIPE 1246_ ITAMK 1251_ ADASK 1256_ KLLKK 1261_ KKGDL 1266_ DTAAV 1271_ KVEFD 1276_ EEFSG 1281_ APVEG 1286_ AGEEA 1291_ LTPSV 1296_ PINKG 1301_ PKPKR 1306_ EKKEP 1311_ GTRVR 1316_ KTPTS 1321_ SGKPS 1326_ AKKVK 1331_ KRNPW 1336_ SDDES 1341_ KSESD 1346_ LEETE 1351_ PVVIP 1356_ RDSLL 1361_ RRAAA 1366_ ERPKY 1371_ TFDFS 1376_ EEEDD 1381_ DADDD 1386_ DDDNN 1391_ DLEEL 1396_ KVKAS 1401_ PITND 1406_ GEDEF 1411_ VPSDG 1416_ LDKDE 1421_ YTFSP 1426_ GKSKA 1431_ TPEKS 1436_ LHDKK 1441_ SQDFG 1446_ NLFSF 1451_ PSYSQ 1456_ KSEDD 1461_ SAKFD 1466_ SNEED 1471_ SASVF 1476_ SPSFG 1481_ LKQTD 1486_ KVPSK 1491_ TVAAK 1496_ KGKPS 1501_ SDTVP 1506_ KPKRA 1511_ PKQKK 1516_ VVEAV 1521_ NSDSD 1526_ SEFGI 1531_ PKKTT 1536_ TPKGK 1541_ GRGAK 1546_ KRKAS 1551_ GSENE 1556_ GDYNP 1561_ GRKTS 1566_ KTTSK 1571_ KPKKT 1576_ SFDQD 1581_ SDVDI 1586_ FPSDF 1591_ PTEPP 1596_ SLPRT 1601_ GRARK 1606_ EVKYF 1611_ AESDE 1616_ EEDDV 1621_DFAMF
1: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. Plays a role in B-cell differentiation