Lamin-B2
1_MSPPS 6_ PGRRR 11_ EQRRP 16_ RAAAT 21_ MATPL 26_ PGRAG 31_ GPATP 36_ LSPTR 41_ LSRLQ 46_ EKEEL 51_ RELND 56_ RLAHY 61_ IDRVR 66_ ALELE 71_ NDRLL 76_ LKISE 81_ KEEVT 86_ TREVS 91_ GIKAL 96_ YESEL 101_ ADARR 106_ VLDET 111_ ARERA 116_ RLQIE 121_ IGKLR 126_ AELDE 131_ VNKSA 136_ KKREG 141_ ELTVA 146_ QGRVK 151_ DLESL 156_ FHRSE 161_ VELAA 166_ ALSDK 171_ RGLES 176_ DVAEL 181_ RAQLA 186_ KAEDG 191_ HAVAK 196_ KQLEK 201_ ETLMR 206_ VDLEN 211_ RCQSL 216_ QEELD 221_ FRKSV 226_ FEEEV 231_ RETRR 236_ RHERR 241_ LVEVD 246_ SSRQQ 251_ EYDFK 256_ MAQAL 261_ EELRS 266_ QHDEQ 271_ VRLYK 276_ LELEQ 281_ TYQAK 286_ LDSAK 291_ LSSDQ 296_ NDKAA 301_ SAARE 306_ ELKEA 311_ RMRLE 316_ SLSYQ 321_ LSGLQ 326_ KQASA 331_ AEDRI 336_ RELEE 341_ AMAGE 346_ RDKFR 351_ KMLDA 356_ KEQEM 361_ TEMRD 366_ VMQQQ 371_ LAEYQ 376_ ELLDV 381_ KLALD 386_ MEINA 391_ YRKLL 396_ EGEEE 401_ RLKLS 406_ PSPSS 411_ RVTVS 416_ RATSS 421_ SSGSL 426_ SATGR 431_ LGRSK 436_ RKRLE 441_ VEEPL 446_ GSGPS 451_ VLGTG 456_ TGGSG 461_ GFHLA 466_ QQASA 471_ SGSVS 476_ IEEID 481_ LEGKF 486_ VQLKN 491_ NSDKD 496_ QSLGN 501_ WRIKR 506_ QVLEG 511_ EEIAY 516_ KFTPK 521_ YILRA 526_ GQMVT 531_ VWAAG 536_ AGVAH 541_ SPPST 546_ LVWKG 551_ QSSWG 556_ TGESF 561_ RTVLV 566_ NADGE 571_ EVAMR 576_ TVKKS 581_ SVMRE 586_ NENGE 591_ EEEEE 596_ AEFGE 601_ EDLFH 606_ QQGDP 611_RTTSR
1: Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane (PubMed:33033404). Lamins provide a framework for the nuclear envelope, bridging the nuclear envelope and chromatin, thereby playing an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics (PubMed:33033404). The structural integrity of the lamina is strictly controlled by the cell cycle, as seen by the disintegration and formation of the nuclear envelope in prophase and telophase, respectively (PubMed:33033404)