Gene name: PTS

Uniprot entry:

Q03393

Protein names:

6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)

Protein sequence:

1_MSTEG 6_ GGRRC 11_ QAQVS 16_ RRISF 21_ SASHR 26_ LYSKF 31_ LSDEE 36_ NLKLF 41_ GKCNN 46_ PNGHG 51_ HNYKV 56_ VVTVH 61_ GEIDP 66_ ATGMV 71_ MNLAD 76_ LKKYM 81_ EEAIM 86_ QPLDH 91_ KNLDM 96_ DVPYF 101_ ADVVS 106_ TTENV 111_ AVYIW 116_ DNLQK 121_ VLPVG 126_ VLYKV 131_ KVYET 136_DNNIV

Protein annotations

Protein functions:

1: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin