Mevalonate kinase (MK) (EC 2.7.1.36)
1_MLSEV 6_ LLVSA 11_ PGKVI 16_ LHGEH 21_ AVVHG 26_ KVALA 31_ VSLNL 36_ RTFLR 41_ LQPHS 46_ NGKVD 51_ LSLPN 56_ IGIKR 61_ AWDVA 66_ RLQSL 71_ DTSFL 76_ EQGDV 81_ TTPTS 86_ EQVEK 91_ LKEVA 96_ GLPDD 101_ CAVTE 106_ RLAVL 111_ AFLYL 116_ YLSIC 121_ RKQRA 126_ LPSLD 131_ IVVWS 136_ ELPPG 141_ AGLGS 146_ SAAYS 151_ VCLAA 156_ ALLTV 161_ CEEIP 166_ NPLKD 171_ GDCVN 176_ RWTKE 181_ DLELI 186_ NKWAF 191_ QGERM 196_ IHGNP 201_ SGVDN 206_ AVSTW 211_ GGALR 216_ YHQGK 221_ ISSLK 226_ RSPAL 231_ QILLT 236_ NTKVP 241_ RNTRA 246_ LVAGV 251_ RNRLL 256_ KFPEI 261_ VAPLL 266_ TSIDA 271_ ISLEC 276_ ERVLG 281_ EMGEA 286_ PAPEQ 291_ YLVLE 296_ ELIDM 301_ NQHHL 306_ NALGV 311_ GHASL 316_ DQLCQ 321_ VTRAR 326_ GLHSK 331_ LTGAG 336_ GGGCG 341_ ITLLK 346_ PGLEQ 351_ PEVEA 356_ TKQAL 361_ TSCGF 366_ DCLET 371_ SIGAP 376_ GVSIH 381_ SATSL 386_ DSRVQ 391_QALDG
1: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis (PubMed:11278915, PubMed:18302342, PubMed:9325256, PubMed:9392419)