Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36)
1_MWLLV 6_ SVILI 11_ SRISS 16_ VGGEA 21_ TFCDF 26_ PKINH 31_ GILYD 36_ EEKYK 41_ PFSQV 46_ PTGEV 51_ FYYSC 56_ EYNFV 61_ SPSKS 66_ FWTRI 71_ TCTEE 76_ GWSPT 81_ PKCLR 86_ LCFFP 91_ FVENG 96_ HSESS 101_ GQTHL 106_ EGDTV 111_ QIICN 116_ TGYRL 121_ QNNEN 126_ NISCV 131_ ERGWS 136_ TPPKC 141_ RSTDT 146_ SCVNP 151_ PTVQN 156_ AHILS 161_ RQMSK 166_ YPSGE 171_ RVRYE 176_ CRSPY 181_ EMFGD 186_ EEVMC 191_ LNGNW 196_ TEPPQ 201_ CKDST 206_ GKCGP 211_ PPPID 216_ NGDIT 221_ SFPLS 226_ VYAPA 231_ SSVEY 236_ QCQNL 241_ YQLEG 246_ NKRIT 251_ CRNGQ 256_ WSEPP 261_ KCLHP 266_ CVISR 271_ EIMEN 276_ YNIAL 281_ RWTAK 286_ QKLYL 291_ RTGES 296_ AEFVC 301_ KRGYR 306_ LSSRS 311_ HTLRT 316_ TCWDG 321_KLEYP
1: Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism