P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein homolog)
1_MHLEG 6_ RDGRR 11_ YPGAP 16_ AVELL 21_ QTSVP 26_ SGLAE 31_ LVAGK 36_ RRLPR 41_ GAGGA 46_ DPSHS 51_ CPRGA 56_ AGQSS 61_ WAPAG 66_ QEFAS 71_ FLTKG 76_ RSHSS 81_ LPQMS 86_ SSRSK 91_ DSCFT 96_ ENTPL 101_ LRNSL 106_ QEKGS 111_ RCIPV 116_ YHPEF 121_ ITAEE 126_ SWEDS 131_ SADWE 136_ RRYLL 141_ SREVS 146_ GLSAS 151_ ASSEK 156_ GDLLD 161_ SPHIR 166_ LRLSK 171_ LRRCV 176_ QWLKV 181_ MGLFA 186_ FVVLC 191_ SILFS 196_ LYPDQ 201_ GKLWQ 206_ LLALS 211_ PLENY 216_ SVNLS 221_ SHVDS 226_ TLLQV 231_ DLAGA 236_ LVASG 241_ PSRPG 246_ REEHI 251_ VVELT 256_ QADAL 261_ GSRWR 266_ RPQQV 271_ THNWT 276_ VYLNP 281_ RRSEH 286_ SVMSR 291_ TFEVL 296_ TRETV 301_ SISIR 306_ ASLQQ 311_ TQAVP 316_ LLMAH 321_ QYLRG 326_ SVETQ 331_ VTIAT 336_ AILAG 341_ VYALI 346_ IFEIV 351_ HRTLA 356_ AMLGS 361_ LAALA 366_ ALAVI 371_ GDRPS 376_ LTHVV 381_ EWIDF 386_ ETLAL 391_ LFGMM 396_ ILVAI 401_ FSETG 406_ FFDYC 411_ AVKAY 416_ RLSRG 421_ RVWAM 426_ IIMLC 431_ LIAAV 436_ LSAFL 441_ DNVTT 446_ MLLFT 451_ PVTIR 456_ LCEVL 461_ NLDPR 466_ QVLIA 471_ EVIFT 476_ NIGGA 481_ ATAIG 486_ DPPNV 491_ IIVSN 496_ QELRK 501_ MGLDF 506_ AGFTA 511_ HMFIG 516_ ICLVL 521_ LVCFP 526_ LLRLL 531_ YWNRK 536_ LYNKE 541_ PSEIV 546_ ELKHE 551_ IHVWR 556_ LTAQR 561_ ISPAS 566_ REETA 571_ VRRLL 576_ LGKVL 581_ ALEHL 586_ LARRL 591_ HTFHR 596_ QISQE 601_ DKNWE 606_ TNIQE 611_ LQKKH 616_ RISDG 621_ ILLAK 626_ CLTVL 631_ GFVIF 636_ MFFLN 641_ SFVPG 646_ IHLDL 651_ GWIAI 656_ LGAIW 661_ LLILA 666_ DIHDF 671_ EIILH 676_ RVEWA 681_ TLLFF 686_ AALFV 691_ LMEAL 696_ AHLHL 701_ IEYVG 706_ EQTAL 711_ LIKMV 716_ PEEQR 721_ LIAAI 726_ VLVVW 731_ VSALA 736_ SSLID 741_ NIPFT 746_ ATMIP 751_ VLLNL 756_ SHDPE 761_ VGLPA 766_ PPLMY 771_ ALAFG 776_ ACLGG 781_ NGTLI 786_ GASAN 791_ VVCAG 796_ IAEQH 801_ GYGFS 806_ FMEFF 811_ RLGFP 816_ MMVVS 821_ CTVGM 826_ CYLLV 831_AHVVV
1: Contributes to a melanosome-specific anion (chloride) current that modulates melanosomal pH for optimal tyrosinase activity required for melanogenesis and the melanosome maturation (PubMed:11310796, PubMed:15262401, PubMed:22234890, PubMed:25513726). One of the components of the mammalian pigmentary system (PubMed:15262401, PubMed:18252222, PubMed:7601462). May serve as a key control point at which ethnic skin color variation is determined. Major determinant of brown and/or blue eye color (PubMed:15262401, PubMed:18252222, PubMed:7601462). Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis (By similarity)