Gene name: EMX2

Uniprot entry:

Q04743

Protein names:

Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles-like protein 2)

Protein sequence:

1_MFQPA 6_ PKRCF 11_ TIESL 16_ VAKDS 21_ PLPAS 26_ RSEDP 31_ IRPAA 36_ LSYAN 41_ SSPIN 46_ PFLNG 51_ FHSAA 56_ AAAAG 61_ RGVYS 66_ NPDLV 71_ FAEAV 76_ SHPPN 81_ PAVPV 86_ HPVPP 91_ PHALA 96_ AHPLP 101_ SSHSP 106_ HPLFA 111_ SQQRD 116_ PSTFY 121_ PWLIH 126_ RYRYL 131_ GHRFQ 136_ GNDTS 141_ PESFL 146_ LHNAL 151_ ARKPK 156_ RIRTA 161_ FSPSQ 166_ LLRLE 171_ HAFEK 176_ NHYVV 181_ GAERK 186_ QLAHS 191_ LSLTE 196_ TQVKV 201_ WFQNR 206_ RTKFK 211_ RQKLE 216_ EEGSD 221_ SQQKK 226_ KGTHH 231_ INRWR 236_ IATKQ 241_ ASPEE 246_IDVTS

Protein annotations

Protein functions:

1: Transcription factor, which in cooperation with EMX1, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combination with OTX1/2 to specify cell fates in the developing central nervous system. In the inner ear, it controls the distribution of GPR156 at hair cell boundaries, and regulates the organization of stereociliary bundles in opposite orientations across the line of polarity reversal (LPR)