Caldesmon (CDM)
1_MDDFE 6_ RRREL 11_ RRQKR 16_ EEMRL 21_ EAERI 26_ AYQRN 31_ DDDEE 36_ EAARE 41_ RRRRA 46_ RQERL 51_ RQKQE 56_ EESLG 61_ QVTDQ 66_ VEVNA 71_ QNSVP 76_ DEEAK 81_ TTTTN 86_ TQVEG 91_ DDEAA 96_ FLERL 101_ ARREE 106_ RRQKR 111_ LQEAL 116_ ERQKE 121_ FDPTI 126_ TDASL 131_ SLPSR 136_ RMQND 141_ TAENE 146_ TTEKE 151_ EKSES 156_ RQERY 161_ EIEET 166_ ETVTK 171_ SYQKN 176_ DWRDA 181_ EENKK 186_ EDKEK 191_ EEEEE 196_ EKPKR 201_ GSIGE 206_ NQVEV 211_ MVEEK 216_ TTESQ 221_ EETVV 226_ MSLKN 231_ GQISS 236_ EEPKQ 241_ EEERE 246_ QGSDE 251_ ISHHE 256_ KMEEE 261_ DKERA 266_ EAERA 271_ RLEAE 276_ ERERI 281_ KAEQD 286_ KKIAD 291_ ERARI 296_ EAEEK 301_ AAAQE 306_ RERRE 311_ AEERE 316_ RMREE 321_ EKRAA 326_ EERQR 331_ IKEEE 336_ KRAAE 341_ ERQRI 346_ KEEEK 351_ RAAEE 356_ RQRIK 361_ EEEKR 366_ AAEER 371_ QRARA 376_ EEEEK 381_ AKVEE 386_ QKRNK 391_ QLEEK 396_ KHAMQ 401_ ETKIK 406_ GEKVE 411_ QKIEG 416_ KWVNE 421_ KKAQE 426_ DKLQT 431_ AVLKK 436_ QGEEK 441_ GTKVQ 446_ AKREK 451_ LQEDK 456_ PTFKK 461_ EEIKD 466_ EKIKK 471_ DKEPK 476_ EEVKS 481_ FMDRK 486_ KGFTE 491_ VKSQN 496_ GEFMT 501_ HKLKH 506_ TENTF 511_ SRPGG 516_ RASVD 521_ TKEAE 526_ GAPQV 531_ EAGKR 536_ LEELR 541_ RRRGE 546_ TESEE 551_ FEKLK 556_ QKQQE 561_ AALEL 566_ EELKK 571_ KREER 576_ RKVLE 581_ EEEQR 586_ RKQEE 591_ ADRKL 596_ REEEE 601_ KRRLK 606_ EEIER 611_ RRAEA 616_ AEKRQ 621_ KMPED 626_ GLSDD 631_ KKPFK 636_ CFTPK 641_ GSSLK 646_ IEERA 651_ EFLNK 656_ SVQKS 661_ SGVKS 666_ THQAA 671_ IVSKI 676_ DSRLE 681_ QYTSA 686_ IEGTK 691_ SAKPT 696_ KPAAS 701_ DLPVP 706_ AEGVR 711_ NIKSM 716_ WEKGN 721_ VFSSP 726_ TAAGT 731_ PNKET 736_ AGLKV 741_ GVSSR 746_ INEWL 751_ TKTPD 756_ GNKSP 761_ APKPS 766_ DLRPG 771_ DVSSK 776_ RNLWE 781_ KQSVD 786_KVTSP
1: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity)