Deuterosome assembly protein 1 (Coiled-coil domain-containing protein 67)
1_MENQA 6_ HNTMG 11_ TSPCE 16_ AELQE 21_ LMEQI 26_ DIMVS 31_ NKKMD 36_ WERKM 41_ RALET 46_ RLDLR 51_ DQELA 56_ NAQTC 61_ LDQKG 66_ QEVGL 71_ LRQKL 76_ DSLEK 81_ CNLAM 86_ TQNYE 91_ GQLQS 96_ LKAQF 101_ SKLTN 106_ NFEKL 111_ RLHQM 116_ KQNKV 121_ PRKEL 126_ PHLKE 131_ EIPFE 136_ LSNLN 141_ QKLEE 146_ FRAKS 151_ REWDK 156_ QEILY 161_ QTHLI 166_ SLDAQ 171_ QKLLS 176_ EKCNQ 181_ FQKQA 186_ QSYQT 191_ QLNGK 196_ KQCLE 201_ DSSSE 206_ IPRLI 211_ CDPDP 216_ NCEIN 221_ ERDEF 226_ IIEKL 231_ KSAVN 236_ EIALS 241_ RNKLQ 246_ DENQK 251_ LLQEL 256_ KMYQR 261_ QCQAM 266_ EAGLS 271_ EVKSE 276_ LQSRD 281_ DLLRI 286_ IEMER 291_ LQLHR 296_ ELLKI 301_ GECQN 306_ AQGNK 311_ TRLES 316_ SYLPS 321_ IKEPE 326_ RKIKE 331_ LFSVM 336_ QDQPN 341_ HEKEL 346_ NKIRS 351_ QLQQV 356_ EEYHN 361_ SEQER 366_ MRNEI 371_ SDLTE 376_ ELHQK 381_ EITIA 386_ TVTKK 391_ AALLE 396_ KQLKM 401_ ELEIK 406_ EKMLA 411_ KQKVS 416_ DMKYK 421_ AVRTE 426_ NTHLK 431_ GMMGD 436_ LDPGE 441_ YMSMD 446_ FTNRE 451_ QSRHT 456_ SINKL 461_ QYENE 466_ RLRND 471_ LAKLH 476_ VNGKS 481_ TWTNQ 486_ NTYEE 491_ TGRYA 496_ YQSQI 501_ KVEQN 506_ EERLS 511_ HDCEP 516_ NRSTM 521_ PPLPP 526_ STFQA 531_ KEMTS 536_ PLVSD 541_ DDVFP 546_ LSPPD 551_ MSFPA 556_ SLAAQ 561_ HFLLE 566_ EEKRA 571_ KELEK 576_ LLNTH 581_ IDELQ 586_ RHTEF 591_ TLNKY 596_SKLKQ
1: Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity)