3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1) (FVT-1) (Short chain dehydrogenase/reductase family 35C member 1)
1_MLLLA 6_ AAFLV 11_ AFVLL 16_ LYMVS 21_ PLISP 26_ KPLAL 31_ PGAHV 36_ VVTGG 41_ SSGIG 46_ KCIAI 51_ ECYKQ 56_ GAFIT 61_ LVARN 66_ EDKLL 71_ QAKKE 76_ IEMHS 81_ INDKQ 86_ VVLCI 91_ SVDVS 96_ QDYNQ 101_ VENVI 106_ KQAQE 111_ KLGPV 116_ DMLVN 121_ CAGMA 126_ VSGKF 131_ EDLEV 136_ STFER 141_ LMSIN 146_ YLGSV 151_ YPSRA 156_ VITTM 161_ KERRV 166_ GRIVF 171_ VSSQA 176_ GQLGL 181_ FGFTA 186_ YSASK 191_ FAIRG 196_ LAEAL 201_ QMEVK 206_ PYNVY 211_ ITVAY 216_ PPDTD 221_ TPGFA 226_ EENRT 231_ KPLET 236_ RLISE 241_ TTSVC 246_ KPEQV 251_ AKQIV 256_ KDAIQ 261_ GNFNS 266_ SLGSD 271_ GYMLS 276_ ALTCG 281_ MAPVT 286_ SITEG 291_ LQQVV 296_ TMGLF 301_ RTIAL 306_ FYLGS 311_ FDSIV 316_ RRCMM 321_ QREKS 326_ENADK
1: Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis