Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha)
1_MAMLR 6_ VQPEA 11_ QAKVD 16_ VFRED 21_ LCTKT 26_ ENLLG 31_ SYFPK 36_ KISEL 41_ DAFLK 46_ EPALN 51_ EANLS 56_ NLKAP 61_ LDIPV 66_ PDPVK 71_ EKEKE 76_ ERKKQ 81_ QEKED 86_ KDEKK 91_ KGEDE 96_ DKGPP 101_ CGPVN 106_ CNEKI 111_ VVLLQ 116_ RLKPE 121_ IKDVI 126_ EQLNL 131_ VTTWL 136_ QLQIP 141_ RIEDG 146_ NNFGV 151_ AVQEK 156_ VFELM 161_ TSLHT 166_ KLEGF 171_ HTQIS 176_ KYFSE 181_ RGDAV 186_ TKAAK 191_ QPHVG 196_ DYRQL 201_ VHELD 206_ EAEYR 211_ DIRLM 216_ VMEIR 221_ NAYAV 226_ LYDII 231_ LKNFE 236_ KLKKP 241_RGETK
1: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome