Phosphatidylinositol-glycan biosynthesis class F protein (PIG-F) (GPI11 homolog)
1_MKDND 6_ IKRLL 11_ YTHLL 16_ CIFSI 21_ ILSVF 26_ IPSLF 31_ LENFS 36_ ILETH 41_ LTWLC 46_ ICSGF 51_ VTAVN 56_ LVLYL 61_ VVKPN 66_ TSSKR 71_ SSLSH 76_ KVTGF 81_ LKCCI 86_ YFLMS 91_ CFSFH 96_ VIFVL 101_ YGAPL 106_ IELAL 111_ ETFLF 116_ AVILS 121_ TFTTV 126_ PCLCL 131_ LGPNL 136_ KAWLR 141_ VFSRN 146_ GVTSI 151_ WENSL 156_ QITTI 161_ SSFVG 166_ AWLGA 171_ LPIPL 176_ DWERP 181_ WQVWP 186_ ISCTL 191_ GATFG 196_ YVAGL 201_ VISPL 206_ WIYWN 211_RKQLT
1: Stabilizing subunit of the ethanolamine phosphate transferase 3 and ethanolamine phosphate transferase 2 complexes that sequentially transfer an ethanolamine phosphate (EtNP) from a phosphatidylethanolamine (PE) to the 6-OH position of the third alpha-1,2-linked mannose and the second alpha-1,6-linked mannose of the alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H6) intermediate to generate a 6-PEtn-alpha-D-Man-(1->2)-6-PEtn-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H8) (PubMed:15632136). Participates in the tenth and eleventh steps of the glycosylphosphatidylinositol-anchor biosynthesis, in association with PIGO and PIGG, respectively (PubMed:15632136, PubMed:33386993)