cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32)
1_MKKSR 6_ SVMTV 11_ MADDN 16_ VKDYF 21_ ECSLS 26_ KSYSS 31_ SSNTL 36_ GIDLW 41_ RGRRC 46_ CSGNL 51_ QLPPL 56_ SQRQS 61_ ERART 66_ PEGDG 71_ ISRPT 76_ TLPLT 81_ TLPSI 86_ AITTV 91_ SQECF 96_ DVENG 101_ PSPGR 106_ SPLDP 111_ QASSS 116_ AGLVL 121_ HATFP 126_ GHSQR 131_ RESFL 136_ YRSDS 141_ DYDLS 146_ PKAMS 151_ RNSSL 156_ PSEQH 161_ GDDLI 166_ VTPFA 171_ QVLAS 176_ LRSVR 181_ NNFTI 186_ LTNLH 191_ GTSNK 196_ RSPAA 201_ SQPPV 206_ SRVNP 211_ QEESY 216_ QKLAM 221_ ETLEE 226_ LDWCL 231_ DQLET 236_ IQTYR 241_ SVSEM 246_ ASNKF 251_ KRMLN 256_ RELTH 261_ LSEMS 266_ RSGNQ 271_ VSEYI 276_ SNTFL 281_ DKQND 286_ VEIPS 291_ PTQKD 296_ REKKK 301_ KQQLM 306_ TQISG 311_ VKKLM 316_ HSSSL 321_ NNTSI 326_ SRFGV 331_ NTENE 336_ DHLAK 341_ ELEDL 346_ NKWGL 351_ NIFNV 356_ AGYSH 361_ NRPLT 366_ CIMYA 371_ IFQER 376_ DLLKT 381_ FRISS 386_ DTFIT 391_ YMMTL 396_ EDHYH 401_ SDVAY 406_ HNSLH 411_ AADVA 416_ QSTHV 421_ LLSTP 426_ ALDAV 431_ FTDLE 436_ ILAAI 441_ FAAAI 446_ HDVDH 451_ PGVSN 456_ QFLIN 461_ TNSEL 466_ ALMYN 471_ DESVL 476_ ENHHL 481_ AVGFK 486_ LLQEE 491_ HCDIF 496_ MNLTK 501_ KQRQT 506_ LRKMV 511_ IDMVL 516_ ATDMS 521_ KHMSL 526_ LADLK 531_ TMVET 536_ KKVTS 541_ SGVLL 546_ LDNYT 551_ DRIQV 556_ LRNMV 561_ HCADL 566_ SNPTK 571_ SLELY 576_ RQWTD 581_ RIMEE 586_ FFQQG 591_ DKERE 596_ RGMEI 601_ SPMCD 606_ KHTAS 611_ VEKSQ 616_ VGFID 621_ YIVHP 626_ LWETW 631_ ADLVQ 636_ PDAQD 641_ ILDTL 646_ EDNRN 651_ WYQSM 656_ IPQSP 661_ SPPLD 666_ EQNRD 671_ CQGLM 676_ EKFQF 681_ ELTLD 686_ EEDSE 691_ GPEKE 696_ GEGHS 701_ YFSST 706_ KTLCV 711_ IDPEN 716_ RDSLG 721_ ETDID 726_ IATED 731_KSPVD
1: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:15260978). May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents