Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
1_MFGLK 6_ RNAVI 11_ GLNLY 16_ CGGAG 21_ LGAGS 26_ GGATR 31_ PGGRL 36_ LATEK 41_ EASAR 46_ REIGG 51_ GEAGA 56_ VIGGS 61_ AGASP 66_ PSTLT 71_ PDSRR 76_ VARPP 81_ PIGAE 86_ VPDVT 91_ ATPAR 96_ LLFFA 101_ PTRRA 106_ APLEE 111_ MEAPA 116_ ADAIM 121_ SPEEE 126_ LDGYE 131_ PEPLG 136_ KRPAV 141_ LPLLE 146_ LVGES 151_ GNNTS 156_ TDGSL 161_ PSTPP 166_ PAEEE 171_ EDELY 176_ RQSLE 181_ IISRY 186_ LREQA 191_ TGAKD 196_ TKPMG 201_ RSGAT 206_ SRKAL 211_ ETLRR 216_ VGDGV 221_ QRNHE 226_ TAFQG 231_ MLRKL 236_ DIKNE 241_ DDVKS 246_ LSRVM 251_ IHVFS 256_ DGVTN 261_ WGRIV 266_ TLISF 271_ GAFVA 276_ KHLKT 281_ INQES 286_ CIEPL 291_ AESIT 296_ DVLVR 301_ TKRDW 306_ LVKQR 311_ GWDGF 316_ VEFFH 321_ VEDLE 326_ GGIRN 331_ VLLAF 336_ AGVAG 341_VGAGL
1: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis