Gene name: MZT1

Uniprot entry:

Q08AG7

Protein names:

Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1)

Protein sequence:

1_MASSS 6_ GAGAA 11_ AAAAA 16_ ANLNA 21_ VRETM 26_ DVLLE 31_ ISRIL 36_ NTGLD 41_ METLS 46_ ICVRL 51_ CEQGI 56_ NPEAL 61_ SSVIK 66_ ELRKA 71_ TEALK 76_AAENM

Protein annotations

Protein functions:

1: Required for the recruitment and the assembly of the gamma-tubulin ring complex (gTuRC) at the centrosome (PubMed:20360068, PubMed:38609661, PubMed:39321809). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed:38609661, PubMed:39321809)