Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
1_MADKE 6_ AAFDD 11_ AVEER 16_ VINEE 21_ YKIWK 26_ KNTPF 31_ LYDLV 36_ MTHAL 41_ EWPSL 46_ TAQWL 51_ PDVTR 56_ PEGKD 61_ FSIHR 66_ LVLGT 71_ HTSDE 76_ QNHLV 81_ IASVQ 86_ LPNDD 91_ AQFDA 96_ SHYDS 101_ EKGEF 106_ GGFGS 111_ VSGKI 116_ EIEIK 121_ INHEG 126_ EVNRA 131_ RYMPQ 136_ NPCII 141_ ATKTP 146_ SSDVL 151_ VFDYT 156_ KHPSK 161_ PDPSG 166_ ECNPD 171_ LRLRG 176_ HQKEG 181_ YGLSW 186_ NPNLS 191_ GHLLS 196_ ASDDH 201_ TICLW 206_ DISAV 211_ PKEGK 216_ VVDAK 221_ TIFTG 226_ HTAVV 231_ EDVSW 236_ HLLHE 241_ SLFGS 246_ VADDQ 251_ KLMIW 256_ DTRSN 261_ NTSKP 266_ SHSVD 271_ AHTAE 276_ VNCLS 281_ FNPYS 286_ EFILA 291_ TGSAD 296_ KTVAL 301_ WDLRN 306_ LKLKL 311_ HSFES 316_ HKDEI 321_ FQVQW 326_ SPHNE 331_ TILAS 336_ SGTDR 341_ RLNVW 346_ DLSKI 351_ GEEQS 356_ PEDAE 361_ DGPPE 366_ LLFIH 371_ GGHTA 376_ KISDF 381_ SWNPN 386_ EPWVI 391_ CSVSE 396_ DNIMQ 401_ VWQMA 406_ ENIYN 411_ DEDPE 416_GSVDP
1: Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (PubMed:10866654). Component of the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair (PubMed:8858152). Component of the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression (PubMed:9150135). Component of the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling (PubMed:16428440, PubMed:28977666, PubMed:39460621). Component of the PRC2 complex, which promotes repression of homeotic genes during development (PubMed:29499137, PubMed:31959557). Component of the NURF (nucleosome remodeling factor) complex (PubMed:14609955, PubMed:15310751)