Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103)
1_MFVEL 6_ NNLLN 11_ TTPDR 16_ AEQGK 21_ LTLLC 26_ DAKTD 31_ GSFLV 36_ HHFLS 41_ FYLKA 46_ NCKVC 51_ FVALI 56_ QSFSH 61_ YSIVG 66_ QKLGV 71_ SLTMA 76_ RERGQ 81_ LVFLE 86_ GLKSA 91_ VDVVF 96_ QAQKE 101_ PHPLQ 106_ FLREA 111_ NAGNL 116_ KPLFE 121_ FVREA 126_ LKPVD 131_ SGEAR 136_ WTYPV 141_ LLVDD 146_ LSVLL 151_ SLGMG 156_ AVAVL 161_ DFIHY 166_ CRATV 171_ CWELK 176_ GNMVV 181_ LVHDS 186_ GDAED 191_ EENDI 196_ LLNGL 201_ SHQSH 206_ LILRA 211_ EGLAT 216_ GFCRD 221_ VHGQL 226_ RILWR 231_ RPSQP 236_ AVHRD 241_ QSFTY 246_ QYKIQ 251_ DKSVS 256_ FFAKG 261_MSPAV
1: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:22854966, PubMed:29332244). Involved in cell migration (By similarity)