Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)
1_MYAVY 6_ KQAHP 11_ PTGLE 16_ FSMYC 21_ NFFNN 26_ SERNL 31_ VVAGT 36_ SQLYV 41_ YRLNR 46_ DAEAL 51_ TKNDR 56_ STEGK 61_ AHREK 66_ LELAA 71_ SFSFF 76_ GNVMS 81_ MASVQ 86_ LAGAK 91_ RDALL 96_ LSFKD 101_ AKLSV 106_ VEYDP 111_ GTHDL 116_ KTLSL 121_ HYFEE 126_ PELRD 131_ GFVQN 136_ VHTPR 141_ VRVDP 146_ DGRCA 151_ AMLVY 156_ GTRLV 161_ VLPFR 166_ RESLA 171_ EEHEG 176_ LVGEG 181_ QRSSF 186_ LPSYI 191_ IDVRA 196_ LDEKL 201_ LNIID 206_ LQFLH 211_ GYYEP 216_ TLLIL 221_ FEPNQ 226_ TWPGR 231_ VAVRQ 236_ DTCSI 241_ VAISL 246_ NITQK 251_ VHPVI 256_ WSLTS 261_ LPFDC 266_ TQALA 271_ VPKPI 276_ GGVVV 281_ FAVNS 286_ LLYLN 291_ QSVPP 296_ YGVAL 301_ NSLTT 306_ GTTAF 311_ PLRTQ 316_ EGVRI 321_ TLDCA 326_ QATFI 331_ SYDKM 336_ VISLK 341_ GGEIY 346_ VLTLI 351_ TDGMR 356_ SVRAF 361_ HFDKA 366_ AASVL 371_ TTSMV 376_ TMEPG 381_ YLFLG 386_ SRLGN 391_ SLLLK 396_ YTEKL 401_ QEPPA 406_ SAVRE 411_ AADKE 416_ EPPSK 421_ KKRVD 426_ ATAGW 431_ SAAGK 436_ SVPQD 441_ EVDEI 446_ EVYGS 451_ EAQSG 456_ TQLAT 461_ YSFEV 466_ CDSIL 471_ NIGPC 476_ ANAAV 481_ GEPAF 486_ LSEEF 491_ QNSPE 496_ PDLEI 501_ VVCSG 506_ HGKNG 511_ ALSVL 516_ QKSIR 521_ PQVVT 526_ TFELP 531_ GCYDM 536_ WTVIA 541_ PVRKE 546_ EEDNP 551_ KGEGT 556_ EQEPS 561_ TTPEA 566_ DDDGR 571_ RHGFL 576_ ILSRE 581_ DSTMI 586_ LQTGQ 591_ EIMEL 596_ DTSGF 601_ ATQGP 606_ TVFAG 611_ NIGDN 616_ RYIVQ 621_ VSPLG 626_ IRLLE 631_ GVNQL 636_ HFIPV 641_ DLGAP 646_ IVQCA 651_ VADPY 656_ VVIMS 661_ AEGHV 666_ TMFLL 671_ KSDSY 676_ GGRHH 681_ RLALH 686_ KPPLH 691_ HQSKV 696_ ITLCL 701_ YRDLS 706_ GMFTT 711_ ESRLG 716_ GARDE 721_ LGGRS 726_ GPEAE 731_ GLGSE 736_ TSPTV 741_ DDEEE 746_ MLYGD 751_ SGSLF 756_ SPSKE 761_ EARRS 766_ SQPPA 771_ DRDPA 776_ PFRAE 781_ PTHWC 786_ LLVRE 791_ NGTME 796_ IYQLP 801_ DWRLV 806_ FLVKN 811_ FPVGQ 816_ RVLVD 821_ SSFGQ 826_ PTTQG 831_ EARRE 836_ EATRQ 841_ GELPL 846_ VKEVL 851_ LVALG 856_ SRQSR 861_ PYLLV 866_ HVDQE 871_ LLIYE 876_ AFPHD 881_ SQLGQ 886_ GNLKV 891_ RFKKV 896_ PHNIN 901_ FREKK 906_ PKPSK 911_ KKAEG 916_ GGAEE 921_ GAGAR 926_ GRVAR 931_ FRYFE 936_ DIYGY 941_ SGVFI 946_ CGPSP 951_ HWLLV 956_ TGRGA 961_ LRLHP 966_ MAIDG 971_ PVDSF 976_ APFHN 981_ VNCPR 986_ GFLYF 991_ NRQGE 996_ LRISV 1001_ LPAYL 1006_ SYDAP 1011_ WPVRK 1016_ IPLRC 1021_ TAHYV 1026_ AYHVE 1031_ SKVYA 1036_ VATST 1041_ NTPCA 1046_ RIPRM 1051_ TGEEK 1056_ EFETI 1061_ ERDER 1066_ YIHPQ 1071_ QEAFS 1076_ IQLIS 1081_ PVSWE 1086_ AIPNA 1091_ RIELQ 1096_ EWEHV 1101_ TCMKT 1106_ VSLRS 1111_ EETVS 1116_ GLKGY 1121_ VAAGT 1126_ CLMQG 1131_ EEVTC 1136_ RGRIL 1141_ IMDVI 1146_ EVVPE 1151_ PGQPL 1156_ TKNKF 1161_ KVLYE 1166_ KEQKG 1171_ PVTAL 1176_ CHCNG 1181_ HLVSA 1186_ IGQKI 1191_ FLWSL 1196_ RASEL 1201_ TGMAF 1206_ IDTQL 1211_ YIHQM 1216_ ISVKN 1221_ FILAA 1226_ DVMKS 1231_ ISLLR 1236_ YQEES 1241_ KTLSL 1246_ VSRDA 1251_ KPLEV 1256_ YSVDF 1261_ MVDNA 1266_ QLGFL 1271_ VSDRD 1276_ RNLMV 1281_ YMYLP 1286_ EAKES 1291_ FGGMR 1296_ LLRRA 1301_ DFHVG 1306_ AHVNT 1311_ FWRTP 1316_ CRGAT 1321_ EGLSK 1326_ KSVVW 1331_ ENKHI 1336_ TWFAT 1341_ LDGGI 1346_ GLLLP 1351_ MQEKT 1356_ YRRLL 1361_ MLQNA 1366_ LTTML 1371_ PHHAG 1376_ LNPRA 1381_ FRMLH 1386_ VDRRT 1391_ LQNAV 1396_ RNVLD 1401_ GELLN 1406_ RYLYL 1411_ STMER 1416_ SELAK 1421_ KIGTT 1426_ PDIIL 1431_ DDLLE 1436_TDRVT
1: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed:14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity)