Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9)
1_MSHQT 6_ GIQAS 11_ EDVKE 16_ IFARA 21_ RNGKY 26_ RLLKI 31_ SIENE 36_ QLVIG 41_ SYSQP 46_ SDSWD 51_ KDYDS 56_ FVLPL 61_ LEDKQ 66_ PCYIL 71_ FRLDS 76_ QNAQG 81_ YEWIF 86_ IAWSP 91_ DHSHV 96_ RQKML 101_ YAATR 106_ ATLKK 111_ EFGGG 116_ HIKDE 121_ VFGTV 126_ KEDVS 131_ LHGYK 136_ KYLLS 141_ QSSPA 146_ PLTAA 151_ EEELR 156_ QIKIN 161_ EVQTD 166_ VGVDT 171_ KHQTL 176_ QGVAF 181_ PISRE 186_ AFQAL 191_ EKLNN 196_ RQLNY 201_ VQLEI 206_ DIKNE 211_ IIILA 216_ NTTNT 221_ ELKDL 226_ PKRIP 231_ KDSAR 236_ YHFFL 241_ YKHSH 246_ EGDYL 251_ ESIVF 256_ IYSMP 261_ GYTCS 266_ IRERM 271_ LYSSC 276_ KSRLL 281_ EIVER 286_ QLQMD 291_ VIRKI 296_ EIDNG 301_ DELTA 306_ DFLYE 311_ EVHPK 316_ QHAHK 321_ QSFAK 326_ PKGPA 331_ GKRGI 336_ RRLIR 341_GPAET
1: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity)