Follistatin-related protein 1 (Follistatin-like protein 1)
1_MWKRW 6_ LALAL 11_ ALVAV 16_ AWVRA 21_ EEELR 26_ SKSKI 31_ CANVF 36_ CGAGR 41_ ECAVT 46_ EKGEP 51_ TCLCI 56_ EQCKP 61_ HKRPV 66_ CGSNG 71_ KTYLN 76_ HCELH 81_ RDACL 86_ TGSKI 91_ QVDYD 96_ GHCKE 101_ KKSVS 106_ PSASP 111_ VVCYQ 116_ SNRDE 121_ LRRRI 126_ IQWLE 131_ AEIIP 136_ DGWFS 141_ KGSNY 146_ SEILD 151_ KYFKN 156_ FDNGD 161_ SRLDS 166_ SEFLK 171_ FVEQN 176_ ETAIN 181_ ITTYP 186_ DQENN 191_ KLLRG 196_ LCVDA 201_ LIELS 206_ DENAD 211_ WKLSF 216_ QEFLK 221_ CLNPS 226_ FNPPE 231_ KKCAL 236_ EDETY 241_ ADGAE 246_ TEVDC 251_ NRCVC 256_ ACGNW 261_ VCTAM 266_ TCDGK 271_ NQKGA 276_ QTQTE 281_ EEMTR 286_ YVQEL 291_ QKHQE 296_ TAEKT 301_KRVST
1: Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (PubMed:22265692, PubMed:29212066). Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (By similarity). Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (By similarity). Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (PubMed:20054002, PubMed:22265692)