Gene name: FOXI1

Uniprot entry:

Q12951

Protein names:

Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead-related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HFH-3) (HNF-3/fork-head homolog 3)

Protein sequence:

1_MSSFD 6_ LPAPS 11_ PPRCS 16_ PQFPS 21_ IGQEP 26_ PEMNL 31_ YYENF 36_ FHPQG 41_ VPSPQ 46_ RPSFE 51_ GGGEY 56_ GATPN 61_ PYLWF 66_ NGPTM 71_ TPPPY 76_ LPGPN 81_ ASPFL 86_ PQAYG 91_ VQRPL 96_ LPSVS 101_ GLGGS 106_ DLGWL 111_ PIPSQ 116_ EELMK 121_ LVRPP 126_ YSYSA 131_ LIAMA 136_ IHGAP 141_ DKRLT 146_ LSQIY 151_ QYVAD 156_ NFPFY 161_ NKSKA 166_ GWQNS 171_ IRHNL 176_ SLNDC 181_ FKKVP 186_ RDEDD 191_ PGKGN 196_ YWTLD 201_ PNCEK 206_ MFDNG 211_ NFRRK 216_ RKRKS 221_ DVSSS 226_ TASLA 231_ LEKTE 236_ SSLPV 241_ DSPKT 246_ TEPQD 251_ ILDGA 256_ SPGGT 261_ TSSPE 266_ KRPSP 271_ PPSGA 276_ PCLNS 281_ FLSSM 286_ TAYVS 291_ GGSPT 296_ SHPLV 301_ TPGLS 306_ PEPSD 311_ KTGQN 316_ SLTFN 321_ SFSPL 326_ TNLSN 331_ HSGGG 336_ DWANP 341_ MPTNM 346_ LSYGG 351_ SVLSQ 356_ FSPHF 361_ YNSVN 366_ TSGVL 371_YPREG

Protein annotations

Protein functions:

1: Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity)