Transcription initiation factor TFIID subunit 10 (STAF28) (Transcription initiation factor TFIID 30 kDa subunit) (TAF(II)30) (TAFII-30) (TAFII30)
1_MSCSG 6_ SGADP 11_ EAAPA 16_ SAASA 21_ PGPAP 26_ PVSAP 31_ AALPS 36_ STAAE 41_ NKASP 46_ AGTAG 51_ GPGAG 56_ AAAGG 61_ TGPLA 66_ ARAGE 71_ PAERR 76_ GAAPV 81_ SAGGA 86_ APPEG 91_ AISNG 96_ VYVLP 101_ SAANG 106_ DVKPV 111_ VSSTP 116_ LVDFL 121_ MQLED 126_ YTPTI 131_ PDAVT 136_ GYYLN 141_ RAGFE 146_ ASDPR 151_ IIRLI 156_ SLAAQ 161_ KFISD 166_ IANDA 171_ LQHCK 176_ MKGTA 181_ SGSSR 186_ SKSKD 191_ RKYTL 196_ TMEDL 201_ TPALS 206_ EYGIN 211_VKKPH
1: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473). TAF10 is also component of the PCAF histone acetylase complex, the TATA-binding protein-free TAF complex (TFTC) and the STAGA transcription coactivator-HAT complex (PubMed:10373431, PubMed:11564863, PubMed:12601814, PubMed:18206972, PubMed:9885574). May regulate cyclin E expression (By similarity)