Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)
1_MVQRM 6_ WAEAA 11_ GPAGG 16_ AEPLF 21_ PGSRR 26_ SRSVW 31_ DAVRL 36_ EVGVP 41_ DSCPV 46_ VLHSF 51_ TQLDP 56_ DLPRP 61_ ESSTQ 66_ EIGEE 71_ LINGV 76_ IYSIS 81_ LRKVQ 86_ LHHGG 91_ NKGQR 96_ WLGYE 101_ NESAL 106_ NLYET 111_ CKVRT 116_ VKAGT 121_ LEKLV 126_ EHLVP 131_ AFQGS 136_ DLSYV 141_ TIFLC 146_ TYRAF 151_ TTTQQ 156_ VLDLL 161_ FKRYG 166_ RCDAL 171_ TASSR 176_ YGCIL 181_ PYSDE 186_ DGGPQ 191_ DQLKN 196_ AISSI 201_ LGTWL 206_ DQYSE 211_ DFCQP 216_ PDFPC 221_ LKQLV 226_ AYVQL 231_ NMPGS 236_ DLERR 241_ AHLLL 246_ AQLEH 251_ SEPIE 256_ AEPEA 261_ LSPVP 266_ ALKPT 271_ PELEL 276_ ALTPA 281_ RAPSP 286_ VPAPA 291_ PEPEP 296_ APTPA 301_ PGSEL 306_ EVAPA 311_ PAPEL 316_ QQAPE 321_ PAVGL 326_ ESAPA 331_ PALEL 336_ EPAPE 341_ QDPAP 346_ SQTLE 351_ LEPAP 356_ APVPS 361_ LQPSW 366_ PSPVV 371_ AENGL 376_ SEEKP 381_ HLLVF 386_ PPDLV 391_ AEQFT 396_ LMDAE 401_ LFKKV 406_ VPYHC 411_ LGSIW 416_ SQRDK 421_ KGKEH 426_ LAPTI 431_ RATVT 436_ QFNSV 441_ ANCVI 446_ TTCLG 451_ NRSTK 456_ APDRA 461_ RVVEH 466_ WIEVA 471_ RECRI 476_ LKNFS 481_ SLYAI 486_ LSALQ 491_ SNSIH 496_ RLKKT 501_ WEDVS 506_ RDSFR 511_ IFQKL 516_ SEIFS 521_ DENNY 526_ SLSRE 531_ LLIKE 536_ GTSKF 541_ ATLEM 546_ NPKRA 551_ QKRPK 556_ ETGII 561_ QGTVP 566_ YLGTF 571_ LTDLV 576_ MLDTA 581_ MKDYL 586_ YGRLI 591_ NFEKR 596_ RKEFE 601_ VIAQI 606_ KLLQS 611_ ACNNY 616_ SIAPD 621_ EQFGA 626_ WFRAV 631_ ERLSE 636_ TESYN 641_ LSCEL 646_ EPPSE 651_ SASNT 656_ LRTKK 661_ NTAIV 666_ KRWSD 671_ RQAPS 676_ TELST 681_ SGSSH 686_ SKSCD 691_ QLRCG 696_ PYLSS 701_ GDIAD 706_ ALSVH 711_ SAGSS 716_ SSDVE 721_ EINIS 726_ FVPES 731_ PDGQE 736_ KKFWE 741_ SASQS 746_ SPETS 751_ GISSA 756_ SSSTS 761_ SSSAS 766_ TTPVA 771_ ATRTH 776_ KRSVS 781_ GLCNS 786_ SSALP 791_ LYNQQ 796_ VGDCC 801_ IIRVS 806_ LDVDN 811_ GNMYK 816_ SILVT 821_ SQDKA 826_ PAVIR 831_ KAMDK 836_ HNLEE 841_ EEPED 846_ YELLQ 851_ ILSDD 856_ RKLKI 861_ PENAN 866_ VFYAM 871_ NSTAN 876_ YDFVL 881_ KKRTF 886_ TKGVK 891_ VKHGA 896_ SSTLP 901_ RMKQK 906_GLKIA
1: Functions as a guanine nucleotide exchange factor (GEF) activating either RalA or RalB GTPases and plays an important role in intracellular transport. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap (By similarity). During bacterial clearance, recognizes 'Lys-33'-linked polyubiquitinated TRAF3 and subsequently mediates assembly of the exocyst complex (PubMed:27438768)