Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6)
1_MNLER 6_ LRKRV 11_ RQYLD 16_ QQQYQ 21_ SALFW 26_ ADKVA 31_ SLSRE 36_ EPQDI 41_ YWLAQ 46_ CLYLT 51_ AQYHR 56_ AAHAL 61_ RSRKL 66_ DKLYE 71_ ACRYL 76_ AARCH 81_ YAAKE 86_ HQQAL 91_ DVLDM 96_ EEPIN 101_ KRLFE 106_ KYLKD 111_ ESGFK 116_ DPSSD 121_ WEMSQ 126_ SSIKS 131_ SICLL 136_ RGKIY 141_ DALDN 146_ RTLAT 151_ YSYKE 156_ ALKLD 161_ VYCFE 166_ AFDLL 171_ TSHHM 176_ LTAQE 181_ EKELL 186_ ESLPL 191_ SKLCN 196_ EEQEL 201_ LRFLF 206_ ENKLK 211_ KYNKP 216_ SETVI 221_ PESVD 226_ GLQEN 231_ LDVVV 236_ SLAER 241_ HYYNC 246_ DFKMC 251_ YKLTS 256_ VVMEK 261_ DPFHA 266_ SCLPV 271_ HIGTL 276_ VELNK 281_ ANELF 286_ YLSHK 291_ LVDLY 296_ PSNPV 301_ SWFAV 306_ GCYYL 311_ MVGHK 316_ NEHAR 321_ RYLSK 326_ ATTLE 331_ KTYGP 336_ AWIAY 341_ GHSFA 346_ VESEH 351_ DQAMA 356_ AYFTA 361_ AQLMK 366_ GCHLP 371_ MLYIG 376_ LEYGL 381_ TNNSK 386_ LAERF 391_ FSQAL 396_ SIAPE 401_ DPFVM 406_ HEVGV 411_ VAFQN 416_ GEWKT 421_ AEKWF 426_ LDALE 431_ KIKAI 436_ GNEVT 441_ VDKWE 446_ PLLNN 451_ LGHVC 456_ RKLKK 461_ YAEAL 466_ DYHRQ 471_ ALVLI 476_ PQNAS 481_ TYSAI 486_ GYIHS 491_ LMGNF 496_ ENAVD 501_ YFHTA 506_ LGLRR 511_ DDTFS 516_ VTMLG 521_ HCIEM 526_ YIGDS 531_ EAYIG 536_ ADIKD 541_ KLKCY 546_ DFDVH 551_ TMKTL 556_ KNIIS 561_ PPWDF 566_ REFEV 571_ EKQTA 576_ EETGL 581_ TPLET 586_ SRKTP 591_ DSRPS 596_ LEETF 601_ EIEMN 606_ ESDMM 611_LETSM
1: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:18485873). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed:18485873). The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (PubMed:29033132)