TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
1_MASSS 6_ GSSPR 11_ PAPDE 16_ NEFPF 21_ GCPPT 26_ VCQDP 31_ KEPRA 36_ LCCAG 41_ CLSEN 46_ PRNGE 51_ DQICP 56_ KCRGE 61_ DLQSI 66_ SPGSR 71_ LRTQE 76_ KAHPE 81_ VAEAG 86_ IGCPF 91_ AGVGC 96_ SFKGS 101_ PQSVQ 106_ EHEVT 111_ SQTSH 116_ LNLLL 121_ GFMKQ 126_ WKARL 131_ GCGLE 136_ SGPMA 141_ LEQNL 146_ SDLQL 151_ QAAVE 156_ VAGDL 161_ EVDCY 166_ RAPCS 171_ ESQEE 176_ LALQH 181_ FMKEK 186_ LLAEL 191_ EGKLR 196_ VFENI 201_ VAVLN 206_ KEVEA 211_ SHLAL 216_ ATSIH 221_ QSQLD 226_ RERIL 231_ SLEQR 236_ VVELQ 241_ QTLAQ 246_ KDQAL 251_ GKLEQ 256_ SLRLM 261_ EEASF 266_ DGTFL 271_ WKITN 276_ VTRRC 281_ HESAC 286_ GRTVS 291_ LFSPA 296_ FYTAK 301_ YGYKL 306_ CLRLY 311_ LNGDG 316_ TGKRT 321_ HLSLF 326_ IVIMR 331_ GEYDA 336_ LLPWP 341_ FRNKV 346_ TFMLL 351_ DQNNR 356_ EHAID 361_ AFRPD 366_ LSSAS 371_ FQRPQ 376_ SETNV 381_ ASGCP 386_ LFFPL 391_ SKLQS 396_ PKHAY 401_ VKDDT 406_ MFLKC 411_IVETS
1: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2