Gene name: DUSP4

Uniprot entry:

Q13115

Protein names:

Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH2) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2)

Protein sequence:

1_MVTME 6_ ELREM 11_ DCSVL 16_ KRLMN 21_ RDENG 26_ GGAGG 31_ SGSHG 36_ TLGLP 41_ SGGKC 46_ LLLDC 51_ RPFLA 56_ HSAGY 61_ ILGSV 66_ NVRCN 71_ TIVRR 76_ RAKGS 81_ VSLEQ 86_ ILPAE 91_ EEVRA 96_ RLRSG 101_ LYSAV 106_ IVYDE 111_ RSPRA 116_ ESLRE 121_ DSTVS 126_ LVVQA 131_ LRRNA 136_ ERTDI 141_ CLLKG 146_ GYERF 151_ SSEYP 156_ EFCSK 161_ TKALA 166_ AIPPP 171_ VPPSA 176_ TEPLD 181_ LGCSS 186_ CGTPL 191_ HDQGG 196_ PVEIL 201_ PFLYL 206_ GSAYH 211_ AARRD 216_ MLDAL 221_ GITAL 226_ LNVSS 231_ DCPNH 236_ FEGHY 241_ QYKCI 246_ PVEDN 251_ HKADI 256_ SSWFM 261_ EAIEY 266_ IDAVK 271_ DCRGR 276_ VLVHC 281_ QAGIS 286_ RSATI 291_ CLAYL 296_ MMKKR 301_ VRLEE 306_ AFEFV 311_ KQRRS 316_ IISPN 321_ FSFMG 326_ QLLQF 331_ ESQVL 336_ ATSCA 341_ AEAAS 346_ PSGPL 351_ RERGK 356_ TPATP 361_ TSQFV 366_ FSFPV 371_ SVGVH 376_ SAPSS 381_ LPYLH 386_SPITT

Protein annotations

Protein functions:

1: Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2