26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
1_MEEGG 6_ RDKAP 11_ VQPQQ 16_ SPAAA 21_ PGGTD 26_ EKPSG 31_ KERRD 36_ AGDKD 41_ KEQEL 46_ SEEDK 51_ QLQDE 56_ LEMLV 61_ ERLGE 66_ KDTSL 71_ YRPAL 76_ EELRR 81_ QIRSS 86_ TTSMT 91_ SVPKP 96_ LKFLR 101_ PHYGK 106_ LKEIY 111_ ENMAP 116_ GENKR 121_ FAADI 126_ ISVLA 131_ MTMSG 136_ ERECL 141_ KYRLV 146_ GSQEE 151_ LASWG 156_ HEYVR 161_ HLAGE 166_ VAKEW 171_ QELDD 176_ AEKVQ 181_ REPLL 186_ TLVKE 191_ IVPYN 196_ MAHNA 201_ EHEAC 206_ DLLME 211_ IEQVD 216_ MLEKD 221_ IDENA 226_ YAKVC 231_ LYLTS 236_ CVNYV 241_ PEPEN 246_ SALLR 251_ CALGV 256_ FRKFS 261_ RFPEA 266_ LRLAL 271_ MLNDM 276_ ELVED 281_ IFTSC 286_ KDVVV 291_ QKQMA 296_ FMLGR 301_ HGVFL 306_ ELSED 311_ VEEYE 316_ DLTEI 321_ MSNVQ 326_ LNSNF 331_ LALAR 336_ ELDIM 341_ EPKVP 346_ DDIYK 351_ THLEN 356_ NRFGG 361_ SGSQV 366_ DSARM 371_ NLASS 376_ FVNGF 381_ VNAAF 386_ GQDKL 391_ LTDDG 396_ NKWLY 401_ KNKDH 406_ GMLSA 411_ AASLG 416_ MILLW 421_ DVDGG 426_ LTQID 431_ KYLYS 436_ SEDYI 441_ KSGAL 446_ LACGI 451_ VNSGV 456_ RNECD 461_ PALAL 466_ LSDYV 471_ LHNSN 476_ TMRLG 481_ SIFGL 486_ GLAYA 491_ GSNRE 496_ DVLTL 501_ LLPVM 506_ GDSKS 511_ SMEVA 516_ GVTAL 521_ ACGMI 526_ AVGSC 531_ NGDVT 536_ STILQ 541_ TIMEK 546_ SETEL 551_ KDTYA 556_ RWLPL 561_ GLGLN 566_ HLGKG 571_ EAIEA 576_ ILAAL 581_ EVVSE 586_ PFRSF 591_ ANTLV 596_ DVCAY 601_ AGSGN 606_ VLKVQ 611_ QLLHI 616_ CSEHF 621_ DSKEK 626_ EEDKD 631_ KKEKK 636_ DKDKK 641_ EAPAD 646_ MGAHQ 651_ GVAVL 656_ GIALI 661_ AMGEE 666_ IGAEM 671_ ALRTF 676_ GHLLR 681_ YGEPT 686_ LRRAV 691_ PLALA 696_ LISVS 701_ NPRLN 706_ ILDTL 711_ SKFSH 716_ DADPE 721_ VSYNS 726_ IFAMG 731_ MVGSG 736_ TNNAR 741_ LAAML 746_ RQLAQ 751_ YHAKD 756_ PNNLF 761_ MVRLA 766_ QGLTH 771_ LGKGT 776_ LTLCP 781_ YHSDR 786_ QLMSQ 791_ VAVAG 796_ LLTVL 801_ VSFLD 806_ VRNII 811_ LGKSH 816_ YVLYG 821_ LVAAM 826_ QPRML 831_ VTFDE 836_ ELRPL 841_ PVSVR 846_ VGQAV 851_ DVVGQ 856_ AGKPK 861_ TITGF 866_ QTHTT 871_ PVLLA 876_ HGERA 881_ ELATE 886_ EFLPV 891_ TPILE 896_ GFVIL 901_RKNPN
1: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair
2: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1