Probable ATP-dependent RNA helicase DDX10 (EC 3.6.4.13) (DEAD box protein 10)
1_MGKTA 6_ NSPGS 11_ GARPD 16_ PVRSF 21_ NRWKK 26_ KHSHR 31_ QNKKK 36_ QLRKQ 41_ LKKPE 46_ WQVER 51_ ESISR 56_ LMQNY 61_ EKINV 66_ NEITR 71_ FSDFP 76_ LSKKT 81_ LKGLQ 86_ EAQYR 91_ LVTEI 96_ QKQTI 101_ GLALQ 106_ GKDVL 111_ GAAKT 116_ GSGKT 121_ LAFLV 126_ PVLEA 131_ LYRLQ 136_ WTSTD 141_ GLGVL 146_ IISPT 151_ RELAY 156_ QTFEV 161_ LRKVG 166_ KNHDF 171_ SAGLI 176_ IGGKD 181_ LKHEA 186_ ERINN 191_ INILV 196_ CTPGR 201_ LLQHM 206_ DETVS 211_ FHATD 216_ LQMLV 221_ LDEAD 226_ RILDM 231_ GFADT 236_ MNAVI 241_ ENLPK 246_ KRQTL 251_ LFSAT 256_ QTKSV 261_ KDLAR 266_ LSLKN 271_ PEYVW 276_ VHEKA 281_ KYSTP 286_ ATLEQ 291_ NYIVC 296_ ELQQK 301_ ISVLY 306_ SFLRS 311_ HLKKK 316_ SIVFF 321_ SSCKE 326_ VQYLY 331_ RVFCR 336_ LRPGV 341_ SILAL 346_ HGRQQ 351_ QMRRM 356_ EVYNE 361_ FVRKR 366_ AAVLF 371_ ATDIA 376_ ARGLD 381_ FPAVN 386_ WVLQF 391_ DCPED 396_ ANTYI 401_ HRAGR 406_ TARYK 411_ EDGEA 416_ LLILL 421_ PSEKA 426_ MVQQL 431_ LQKKV 436_ PVKEI 441_ KINPE 446_ KLIDV 451_ QKKLE 456_ SILAQ 461_ DQDLK 466_ ERAQR 471_ CFVSY 476_ VRSVY 481_ LMKDK 486_ EVFDV 491_ SKLPI 496_ PEYAL 501_ SLGLA 506_ VAPRV 511_ RFLQK 516_ MQKQP 521_ TKELV 526_ RSQAD 531_ KVIEP 536_ RAPSL 541_ TNDEV 546_ EEFRA 551_ YFNEK 556_ MSILQ 561_ KGGKR 566_ LEGTE 571_ HRQDN 576_ DTGNE 581_ EQEEE 586_ EDDEE 591_ EMEEK 596_ LAKAK 601_ GSQAP 606_ SLPNT 611_ SEAQK 616_ IKEVP 621_ TQFLD 626_ RDEEE 631_ EDADF 636_ LKVKR 641_ HNVFG 646_ LDLKD 651_ EKTLQ 656_ KKEPS 661_ KSSIK 666_ KKMTK 671_ VAEAK 676_ KVMKR 681_ NFKVN 686_ KKITF 691_ TDEGE 696_ LVQQW 701_ PQMQK 706_ SAIKD 711_ AEEDD 716_ DTGGI 721_ NLHKA 726_ KERLQ 731_ EEDKF 736_ DKEEY 741_ RKKIK 746_ AKHRE 751_ KRLKE 756_ REARR 761_ EANKR 766_ QAKAK 771_ DEEEA 776_ FLDWS 781_ DDDDD 786_ DDDGF 791_ DPSTL 796_ PDPDK 801_ YRSSE 806_ DSDSE 811_ DMENK 816_ ISDTK 821_ KKQGM 826_ KKRSN 831_ SEVED 836_ VGPTS 841_ HNRKK 846_ ARWDT 851_ LEPLD 856_ TGLSL 861_ AEDEE 866_LVLHL
1: Putative ATP-dependent RNA helicase that plays various role in innate immunity or inflammation. Plays a role in the enhancement of AIM2-induced inflammasome activation by interacting with AIM2 and stabilizing its protein level (PubMed:32519665). Negatively regulates viral infection by promoting interferon beta production and interferon stimulated genes/ISGs expression (PubMed:36779599)