Gene name: SRSF6

Uniprot entry:

Q13247

Protein names:

Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)

Protein sequence:

1_MPRVY 6_ IGRLS 11_ YNVRE 16_ KDIQR 21_ FFSGY 26_ GRLLE 31_ VDLKN 36_ GYGFV 41_ EFEDS 46_ RDADD 51_ AVYEL 56_ NGKEL 61_ CGERV 66_ IVEHA 71_ RGPRR 76_ DRDGY 81_ SYGSR 86_ SGGGG 91_ YSSRR 96_ TSGRD 101_ KYGPP 106_ VRTEY 111_ RLIVE 116_ NLSSR 121_ CSWQD 126_ LKDFM 131_ RQAGE 136_ VTYAD 141_ AHKER 146_ TNEGV 151_ IEFRS 156_ YSDMK 161_ RALDK 166_ LDGTE 171_ INGRN 176_ IRLIE 181_ DKPRT 186_ SHRRS 191_ YSGSR 196_ SRSRS 201_ RRRSR 206_ SRSRR 211_ SSRSR 216_ SRSIS 221_ KSRSR 226_ SRSRS 231_ KGRSR 236_ SRSKG 241_ RKSRS 246_ KSKSK 251_ PKSDR 256_ GSHSH 261_ SRSRS 266_ KDEYE 271_ KSRSR 276_ SRSRS 281_ PKENG 286_ KGDIK 291_ SKSRS 296_ RSQSR 301_ SNSPL 306_ PVPPS 311_ KARSV 316_ SPPPK 321_ RATSR 326_ SRSRS 331_ RSKSR 336_SRSRS

Protein annotations

Protein functions:

1: Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing