Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)]
1_MAPRR 6_ ARGCR 11_ TLGLP 16_ ALLLL 21_ LLLRP 26_ PATRG 31_ ITCPP 36_ PMSVE 41_ HADIW 46_ VKSYS 51_ LYSRE 56_ RYICN 61_ SGFKR 66_ KAGTS 71_ SLTEC 76_ VLNKA 81_ TNVAH 86_ WTTPS 91_ LKCIR 96_ DPALV 101_ HQRPA 106_ PPSTV 111_ TTAGV 116_ TPQPE 121_ SLSPS 126_ GKEPA 131_ ASSPS 136_ SNNTA 141_ ATTAA 146_ IVPGS 151_ QLMPS 156_ KSPST 161_ GTTEI 166_ SSHES 171_ SHGTP 176_ SQTTA 181_ KNWEL 186_ TASAS 191_ HQPPG 196_ VYPQG 201_ HSDTT 206_ VAIST 211_ STVLL 216_ CGLSA 221_ VSLLA 226_ CYLKS 231_ RQTPP 236_ LASVE 241_ MEAME 246_ ALPVT 251_ WGTSS 256_ RDEDL 261_ENCSH
1: High-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed:15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed:15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed:10480910)
2: Does not bind IL15
3: Does not bind IL15
4: Does not bind IL15
5: Does not bind IL15