Nuclear body protein SP140 (Lymphoid-restricted homolog of Sp100) (LYSp100) (Nuclear autoantigen Sp-140) (Speckled 140 kDa)
1_MAQQG 6_ QQGQM 11_ ASGDS 16_ NLNFR 21_ MVAEI 26_ QNVEG 31_ QNLQE 36_ QVCPE 41_ PIFRF 46_ FRENK 51_ VEIAS 56_ AITRP 61_ FPFLM 66_ GLRDR 71_ SFISE 76_ QMYEH 81_ FQEAF 86_ RNLVP 91_ VTRVM 96_ YCVLS 101_ ELEKT 106_ FGWSH 111_ LEALF 116_ SRINL 121_ MAYPD 126_ LNEIY 131_ RSFQN 136_ VCYEH 141_ SPLQM 146_ NNVND 151_ LEDRP 156_ RLLPY 161_ GKQEN 166_ SNACH 171_ EMDDI 176_ AVPQE 181_ ALSSS 186_ PRCEP 191_ GFSSE 196_ SCEQL 201_ ALPKA 206_ GGGDA 211_ EDAPS 216_ LLPGG 221_ GVSCK 226_ LAIQI 231_ DEGES 236_ EEMPK 241_ LLPYD 246_ TEVLE 251_ SNGMI 256_ DAART 261_ YSTAP 266_ GEKQG 271_ EEEGR 276_ NSPRK 281_ RNQDK 286_ EKYQE 291_ SPEGR 296_ DKETF 301_ DLKTP 306_ QVTNE 311_ GEPEK 316_ GLCLL 321_ PGEGE 326_ EGSDD 331_ CSEMC 336_ DGEEP 341_ QEASS 346_ SLARC 351_ GSVSC 356_ LSAET 361_ FDLKT 366_ PQVTN 371_ EGEPE 376_ KELSL 381_ LPGEG 386_ EEGSD 391_ DCSEM 396_ CDGEE 401_ RQEAS 406_ SSLAR 411_ RGSVS 416_ SELEN 421_ HPMNE 426_ EGESE 431_ ELASS 436_ LLYDN 441_ VPGAE 446_ QSAYE 451_ NEKCS 456_ CVMCF 461_ SEEVP 466_ GSPEA 471_ RTESD 476_ QACGT 481_ MDTVD 486_ IANNS 491_ TLGKP 496_ KRKRR 501_ KKRGH 506_ GWSRM 511_ RMRRQ 516_ ENSQQ 521_ NDNSK 526_ ADGQV 531_ VSSEK 536_ KANVN 541_ LKDLS 546_ KIRGR 551_ KRGKP 556_ GTRFT 561_ QSDRA 566_ AQKRV 571_ RSRAS 576_ RKHKD 581_ ETVDF 586_ KAPLL 591_ PVTCG 596_ GVKGI 601_ LHKKK 606_ LQQGI 611_ LVKCI 616_ QTEDG 621_ KWFTP 626_ TEFEI 631_ KGGHA 636_ RSKNW 641_ RLSVR 646_ CGGWP 651_ LRWLM 656_ ENGFL 661_ PDPPR 666_ IRYRK 671_ KKRIL 676_ KSQNN 681_ SSVDP 686_ CMRNL 691_ DECEV 696_ CRDGG 701_ ELFCC 706_ DTCSR 711_ VFHED 716_ CHIPP 721_ VEAER 726_ TPWNC 731_ IFCRM 736_ KESPG 741_ SQQCC 746_ QESEV 751_ LERQM 756_ CPEEQ 761_ LKCEF 766_ LLLKV 771_ YCCSE 776_ SSFFA 781_ KIPYY 786_ YYIRE 791_ ACQGL 796_ KEPMW 801_ LDKIK 806_ KRLNE 811_ HGYPQ 816_ VEGFV 821_ QDMRL 826_ IFQNH 831_ RASYK 836_ YKDFG 841_ QMGFR 846_ LEAEF 851_ EKNFK 856_ EVFAI 861_QETNG
1: Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body (PubMed:8910577). May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection (PubMed:8910577). May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails (PubMed:24267382)