AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP)
1_MSAAP 6_ AYSED 11_ KGGSA 16_ GPGEP 21_ EYGHD 26_ PASGG 31_ IFSSD 36_ YKRHD 41_ DLKEM 46_ LDTNK 51_ DSLKL 56_ EAMKR 61_ IVAMI 66_ ARGKN 71_ ASDLF 76_ PAVVK 81_ NVACK 86_ NIEVK 91_ KLVYV 96_ YLVRY 101_ AEEQQ 106_ DLALL 111_ SISTF 116_ QRGLK 121_ DPNQL 126_ IRASA 131_ LRVLS 136_ SIRVP 141_ IIVPI 146_ MMLAI 151_ KEAAS 156_ DMSPY 161_ VRKTA 166_ AHAIP 171_ KLYSL 176_ DSDQK 181_ DQLIE 186_ VIEKL 191_ LADKT 196_ TLVAG 201_ SVVMA 206_ FEEVC 211_ PERID 216_ LIHKN 221_ YRKLC 226_ NLLID 231_ VEEWG 236_ QVVII 241_ SMLTR 246_ YARTQ 251_ FLSPT 256_ QNESL 261_ LEENA 266_ EKAFY 271_ GSEED 276_ EAKGA 281_ GSEET 286_ AAAAA 291_ PSRKP 296_ YVMDP 301_ DHRLL 306_ LRNTK 311_ PLLQS 316_ RSAAV 321_ VMAVA 326_ QLYFH 331_ LAPKA 336_ EVGVI 341_ AKALV 346_ RLLRS 351_ HSEVQ 356_ YVVLQ 361_ NVATM 366_ SIKRR 371_ GMFEP 376_ YLKSF 381_ YIRST 386_ DPTQI 391_ KILKL 396_ EVLTN 401_ LANET 406_ NIPTV 411_ LREFQ 416_ TYIRS 421_ MDKDF 426_ VAATI 431_ QAIGR 436_ CATNI 441_ GRVRD 446_ TCLNG 451_ LVQLL 456_ SNRDE 461_ LVVAE 466_ SVVVI 471_ KKLLQ 476_ MQPAQ 481_ HGEII 486_ KHLAK 491_ LTDNI 496_ QVPMA 501_ RASIL 506_ WLIGE 511_ YCEHV 516_ PRIAP 521_ DVLRK 526_ MAKSF 531_ TAEED 536_ IVKLQ 541_ VINLA 546_ AKLYL 551_ TNSKQ 556_ TKLLT 561_ QYVLS 566_ LAKYD 571_ QNYDI 576_ RDRAR 581_ FTRQL 586_ IVPSE 591_ QGGAL 596_ SRHAK 601_ KLFLA 606_ PKPAP 611_ VLESS 616_ FKDRD 621_ HFQLG 626_ SLSHL 631_ LNAKA 636_ TGYQE 641_ LPDWP 646_ EEAPD 651_ PSVRN 656_ VEVPE 661_ WTKCS 666_ NREKR 671_ KEKEK 676_ PFYSD 681_ SEGES 686_ GPTES 691_ ADSDP 696_ ESESE 701_ SDSKS 706_ SSESG 711_ SGESS 716_ SESDN 721_ EDQDE 726_ DEEKG 731_ RGSES 736_ EQSEE 741_ DGKRK 746_ TKKKV 751_ PERKG 756_ EASSS 761_ DEGSD 766_ SSSSS 771_ SESEM 776_ TSESE 781_ EEQLE 786_ PASWS 791_ RKTPP 796_ SSKSA 801_ PATKE 806_ ISLLD 811_ LEDFT 816_ PPSVQ 821_ PVSPP 826_ AIVST 831_ SLAAD 836_ LEGLT 841_ LTDST 846_ LVPSL 851_ LSPVS 856_ GVGRQ 861_ ELLHR 866_ VAGEG 871_ LAVDY 876_ TFSRQ 881_ PFSGD 886_ PHMVS 891_ VHIHF 896_ SNSSD 901_ TPIKG 906_ LHVGT 911_ PKLPA 916_ GISIQ 921_ EFPEI 926_ ESLAP 931_ GESAT 936_ AVMGI 941_ NFCDS 946_ TQAAN 951_ FQLCT 956_ QTRQF 961_ YVSIQ 966_ PPVGE 971_ LMAPV 976_ FMSEN 981_ EFKKE 986_ QGKLM 991_ GMNEI 996_ TEKLM 1001_ LPDTC 1006_ RSDHI 1011_ VVQKV 1016_ TATAN 1021_ LGRVP 1026_ CGTSD 1031_ EYRFA 1036_ GRTLT 1041_ GGSLV 1046_ LLTLD 1051_ ARPAG 1056_ AAQLT 1061_ VNSEK 1066_ MVIGT 1071_ MLVKD 1076_VIQAL
1: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals