Unconventional myosin-VIIa
1_MVILQ 6_ QGDHV 11_ WMDLR 16_ LGQEF 21_ DVPIG 26_ AVVKL 31_ CDSGQ 36_ VQVVD 41_ DEDNE 46_ HWISP 51_ QNATH 56_ IKPMH 61_ PTSVH 66_ GVEDM 71_ IRLGD 76_ LNEAG 81_ ILRNL 86_ LIRYR 91_ DHLIY 96_ TYTGS 101_ ILVAV 106_ NPYQL 111_ LSIYS 116_ PEHIR 121_ QYTNK 126_ KIGEM 131_ PPHIF 136_ AIADN 141_ CYFNM 146_ KRNSR 151_ DQCCI 156_ ISGES 161_ GAGKT 166_ ESTKL 171_ ILQFL 176_ AAISG 181_ QHSWI 186_ EQQVL 191_ EATPI 196_ LEAFG 201_ NAKTI 206_ RNDNS 211_ SRFGK 216_ YIDIH 221_ FNKRG 226_ AIEGA 231_ KIEQY 236_ LLEKS 241_ RVCRQ 246_ ALDER 251_ NYHVF 256_ YCMLE 261_ GMSED 266_ QKKKL 271_ GLGQA 276_ SDYNY 281_ LAMGN 286_ CITCE 291_ GRVDS 296_ QEYAN 301_ IRSAM 306_ KVLMF 311_ TDTEN 316_ WEISK 321_ LLAAI 326_ LHLGN 331_ LQYEA 336_ RTFEN 341_ LDACE 346_ VLFSP 351_ SLATA 356_ ASLLE 361_ VNPPD 366_ LMSCL 371_ TSRTL 376_ ITRGE 381_ TVSTP 386_ LSREQ 391_ ALDVR 396_ DAFVK 401_ GIYGR 406_ LFVWI 411_ VDKIN 416_ AAIYK 421_ PPSQD 426_ VKNSR 431_ RSIGL 436_ LDIFG 441_ FENFA 446_ VNSFE 451_ QLCIN 456_ FANEH 461_ LQQFF 466_ VRHVF 471_ KLEQE 476_ EYDLE 481_ SIDWL 486_ HIEFT 491_ DNQDA 496_ LDMIA 501_ NKPMN 506_ IISLI 511_ DEESK 516_ FPKGT 521_ DTTML 526_ HKLNS 531_ QHKLN 536_ ANYIP 541_ PKNNH 546_ ETQFG 551_ INHFA 556_ GIVYY 561_ ETQGF 566_ LEKNR 571_ DTLHG 576_ DIIQL 581_ VHSSR 586_ NKFIK 591_ QIFQA 596_ DVAMG 601_ AETRK 606_ RSPTL 611_ SSQFK 616_ RSLEL 621_ LMRTL 626_ GACQP 631_ FFVRC 636_ IKPNE 641_ FKKPM 646_ LFDRH 651_ LCVRQ 656_ LRYSG 661_ MMETI 666_ RIRRA 671_ GYPIR 676_ YSFVE 681_ FVERY 686_ RVLLP 691_ GVKPA 696_ YKQGD 701_ LRGTC 706_ QRMAE 711_ AVLGT 716_ HDDWQ 721_ IGKTK 726_ IFLKD 731_ HHDML 736_ LEVER 741_ DKAIT 746_ DRVIL 751_ LQKVI 756_ RGFKD 761_ RSNFL 766_ KLKNA 771_ ATLIQ 776_ RHWRG 781_ HNCRK 786_ NYGLM 791_ RLGFL 796_ RLQAL 801_ HRSRK 806_ LHQQY 811_ RLARQ 816_ RIIQF 821_ QARCR 826_ AYLVR 831_ KAFRH 836_ RLWAV 841_ LTVQA 846_ YARGM 851_ IARRL 856_ HQRLR 861_ AEYLW 866_ RLEAE 871_ KMRLA 876_ EEEKL 881_ RKEMS 886_ AKKAK 891_ EEAER 896_ KHQER 901_ LAQLA 906_ REDAE 911_ RELKE 916_ KEAAR 921_ RKKEL 926_ LEQME 931_ RARHE 936_ PVNHS 941_ DMVDK 946_ MFGFL 951_ GTSGG 956_ LPGQE 961_ GQAPS 966_ GFEDL 971_ ERGRR 976_ EMVEE 981_ DLDAA 986_ LPLPD 991_ EDEED 996_ LSEYK 1001_ FAKFA 1006_ ATYFQ 1011_ GTTTH 1016_ SYTRR 1021_ PLKQP 1026_ LLYHD 1031_ DEGDQ 1036_ LAALA 1041_ VWITI 1046_ LRFMG 1051_ DLPEP 1056_ KYHTA 1061_ MSDGS 1066_ EKIPV 1071_ MTKIY 1076_ ETLGK 1081_ KTYKR 1086_ ELQAL 1091_ QGEGE 1096_ AQLPE 1101_ GQKKS 1106_ SVRHK 1111_ LVHLT 1116_ LKKKS 1121_ KLTEE 1126_ VTKRL 1131_ HDGES 1136_ TVQGN 1141_ SMLED 1146_ RPTSN 1151_ LEKLH 1156_ FIIGN 1161_ GILRP 1166_ ALRDE 1171_ IYCQI 1176_ SKQLT 1181_ HNPSK 1186_ SSYAR 1191_ GWILV 1196_ SLCVG 1201_ CFAPS 1206_ EKFVK 1211_ YLRNF 1216_ IHGGP 1221_ PGYAP 1226_ YCEER 1231_ LRRTF 1236_ VNGTR 1241_ TQPPS 1246_ WLELQ 1251_ ATKSK 1256_ KPIML 1261_ PVTFM 1266_ DGTTK 1271_ TLLTD 1276_ SATTA 1281_ KELCN 1286_ ALADK 1291_ ISLKD 1296_ RFGFS 1301_ LYIAL 1306_ FDKVS 1311_ SLGSG 1316_ SDHVM 1321_ DAISQ 1326_ CEQYA 1331_ KEQGA 1336_ QERNA 1341_ PWRLF 1346_ FRKEV 1351_ FTPWH 1356_ SPSED 1361_ NVATN 1366_ LIYQQ 1371_ VVRGV 1376_ KFGEY 1381_ RCEKE 1386_ DDLAE 1391_ LASQQ 1396_ YFVDY 1401_ GSEMI 1406_ LERLL 1411_ NLVPT 1416_ YIPDR 1421_ EITPL 1426_ KTLEK 1431_ WAQLA 1436_ IAAHK 1441_ KGIYA 1446_ QRRTD 1451_ AQKVK 1456_ EDVVS 1461_ YARFK 1466_ WPLLF 1471_ SRFYE 1476_ AYKFS 1481_ GPSLP 1486_ KNDVI 1491_ VAVNW 1496_ TGVYF 1501_ VDEQE 1506_ QVLLE 1511_ LSFPE 1516_ IMAVS 1521_ SSREC 1526_ RVWLS 1531_ LGCSD 1536_ LGCAA 1541_ PHSGW 1546_ AGLTP 1551_ AGPCS 1556_ PCWSC 1561_ RGAKT 1566_ TAPSF 1571_ TLATI 1576_ KGDEY 1581_ TFTSS 1586_ NAEDI 1591_ RDLVV 1596_ TFLEG 1601_ LRKRS 1606_ KYVVA 1611_ LQDNP 1616_ NPAGE 1621_ ESGFL 1626_ SFAKG 1631_ DLIIL 1636_ DHDTG 1641_ EQVMN 1646_ SGWAN 1651_ GINER 1656_ TKQRG 1661_ DFPTD 1666_ SVYVM 1671_ PTVTM 1676_ PPREI 1681_ VALVT 1686_ MTPDQ 1691_ RQDVV 1696_ RLLQL 1701_ RTAEP 1706_ EVRAK 1711_ PYTLE 1716_ EFSYD 1721_ YFRPP 1726_ PKHTL 1731_ SRVMV 1736_ SKARG 1741_ KDRLW 1746_ SHTRE 1751_ PLKQA 1756_ LLKKL 1761_ LGSEE 1766_ LSQEA 1771_ CLAFI 1776_ AVLKY 1781_ MGDYP 1786_ SKRTR 1791_ SVNEL 1796_ TDQIF 1801_ EGPLK 1806_ AEPLK 1811_ DEAYV 1816_ QILKQ 1821_ LTDNH 1826_ IRYSE 1831_ ERGWE 1836_ LLWLC 1841_ TGLFP 1846_ PSNIL 1851_ LPHVQ 1856_ RFLQS 1861_ RKHCP 1866_ LAIDC 1871_ LQRLQ 1876_ KALRN 1881_ GSRKY 1886_ PPHLV 1891_ EVEAI 1896_ QHKTT 1901_ QIFHK 1906_ VYFPD 1911_ DTDEA 1916_ FEVES 1921_ STKAK 1926_ DFCQN 1931_ IATRL 1936_ LLKSS 1941_ EGFSL 1946_ FVKIA 1951_ DKVLS 1956_ VPEND 1961_ FFFDF 1966_ VRHLT 1971_ DWIKK 1976_ ARPIK 1981_ DGIVP 1986_ SLTYQ 1991_ VFFMK 1996_ KLWTT 2001_ TVPGK 2006_ DPMAD 2011_ SIFHY 2016_ YQELP 2021_ KYLRG 2026_ YHKCT 2031_ REEVL 2036_ QLGAL 2041_ IYRVK 2046_ FEEDK 2051_ SYFPS 2056_ IPKLL 2061_ RELVP 2066_ QDLIR 2071_ QVSPD 2076_ DWKRS 2081_ IVAYF 2086_ NKHAG 2091_ KSKEE 2096_ AKLAF 2101_ LKLIF 2106_ KWPTF 2111_ GSAFF 2116_ EVKQT 2121_ TEPNF 2126_ PEILL 2131_ IAINK 2136_ YGVSL 2141_ IDPKT 2146_ KDILT 2151_ THPFT 2156_ KISNW 2161_ SSGNT 2166_ YFHIT 2171_ IGNLV 2176_ RGSKL 2181_ LCETS 2186_ LGYKM 2191_ DDLLT 2196_ SYISQ 2201_ MLTAM 2206_SKQRG
1: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing