Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead-related transcription factor 8) (FREAC-8)
1_MAGRS 6_ DMDPP 11_ AAFSG 16_ FPALP 21_ AVAPS 26_ GPPPS 31_ PLAGA 36_ EPGRE 41_ PEEAA 46_ AGRGE 51_ AAPTP 56_ APGPG 61_ RRRRR 66_ PLQRG 71_ KPPYS 76_ YIALI 81_ AMALA 86_ HAPGR 91_ RLTLA 96_ AIYRF 101_ ITERF 106_ AFYRD 111_ SPRKW 116_ QNSIR 121_ HNLTL 126_ NDCFV 131_ KVPRE 136_ PGNPG 141_ KGNYW 146_ TLDPA 151_ AADMF 156_ DNGSF 161_ LRRRK 166_ RFKRA 171_ ELPAH 176_ AAAAP 181_ GPPLP 186_ FPYAP 191_ YAPAP 196_ GPALL 201_ VPPPS 206_ AGPGP 211_ SPPAR 216_ LFSVD 221_ SLVNL 226_ QPELA 231_ GLGAP 236_ EPPCC 241_ AAPDA 246_ AAAAF 251_ PPCAA 256_ AASPP 261_ LYSQV 266_ PDRLV 271_ LPATR 276_ PGPGP 281_ LPAEP 286_ LLALA 291_ GPAAA 296_ LGPLS 301_ PGEAY 306_ LRQPG 311_FASGL
1: Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149)