Frizzled-5 (Fz-5) (hFz5) (FzE5)
1_MARPD 6_ PSAPP 11_ SLLLL 16_ LLAQL 21_ VGRAA 26_ AASKA 31_ PVCQE 36_ ITVPM 41_ CRGIG 46_ YNLTH 51_ MPNQF 56_ NHDTQ 61_ DEAGL 66_ EVHQF 71_ WPLVE 76_ IQCSP 81_ DLRFF 86_ LCSMY 91_ TPICL 96_ PDYHK 101_ PLPPC 106_ RSVCE 111_ RAKAG 116_ CSPLM 121_ RQYGF 126_ AWPER 131_ MSCDR 136_ LPVLG 141_ RDAEV 146_ LCMDY 151_ NRSEA 156_ TTAPP 161_ RPFPA 166_ KPTLP 171_ GPPGA 176_ PASGG 181_ ECPAG 186_ GPFVC 191_ KCREP 196_ FVPIL 201_ KESHP 206_ LYNKV 211_ RTGQV 216_ PNCAV 221_ PCYQP 226_ SFSAD 231_ ERTFA 236_ TFWIG 241_ LWSVL 246_ CFIST 251_ STTVA 256_ TFLID 261_ MERFR 266_ YPERP 271_ IIFLS 276_ ACYLC 281_ VSLGF 286_ LVRLV 291_ VGHAS 296_ VACSR 301_ EHNHI 306_ HYETT 311_ GPALC 316_ TIVFL 321_ LVYFF 326_ GMASS 331_ IWWVI 336_ LSLTW 341_ FLAAG 346_ MKWGN 351_ EAIAG 356_ YAQYF 361_ HLAAW 366_ LIPSV 371_ KSITA 376_ LALSS 381_ VDGDP 386_ VAGIC 391_ YVGNQ 396_ NLNSL 401_ RGFVL 406_ GPLVL 411_ YLLVG 416_ TLFLL 421_ AGFVS 426_ LFRIR 431_ SVIKQ 436_ GGTKT 441_ DKLEK 446_ LMIRI 451_ GIFTL 456_ LYTVP 461_ ASIVV 466_ ACYLY 471_ EQHYR 476_ ESWEA 481_ ALTCA 486_ CPGHD 491_ TGQPR 496_ AKPEY 501_ WVLML 506_ KYFMC 511_ LVVGI 516_ TSGVW 521_ IWSGK 526_ TVESW 531_ RRFTS 536_ RCCCR 541_ PRRGH 546_ KSGGA 551_ MAAGD 556_ YPEAS 561_ AALTG 566_ RTGPP 571_ GPAAT 576_YHKQV
1: Receptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By similarity). In neurons, activation by WNT7A promotes formation of synapses (PubMed:20530549). May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization (By similarity). Plays a role in ocular development (PubMed:26908622)