V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)
1_MGSMF 6_ RSEEV 11_ ALVQL 16_ FLPTA 21_ AAYTC 26_ VSRLG 31_ ELGLV 36_ EFRDL 41_ NASVS 46_ AFQRR 51_ FVVDV 56_ RRCEE 61_ LEKTF 66_ TFLQE 71_ EVRRA 76_ GLVLP 81_ PPKGR 86_ LPAPP 91_ PRDLL 96_ RIQEE 101_ TERLA 106_ QELRD 111_ VRGNQ 116_ QALRA 121_ QLHQL 126_ QLHAA 131_ VLRQG 136_ HEPQL 141_ AAAHT 146_ DGASE 151_ RTPLL 156_ QAPGG 161_ PHQDL 166_ RVNFV 171_ AGAVE 176_ PHKAP 181_ ALERL 186_ LWRAC 191_ RGFLI 196_ ASFRE 201_ LEQPL 206_ EHPVT 211_ GEPAT 216_ WMTFL 221_ ISYWG 226_ EQIGQ 231_ KIRKI 236_ TDCFH 241_ CHVFP 246_ FLQQE 251_ EARLG 256_ ALQQL 261_ QQQSQ 266_ ELQEV 271_ LGETE 276_ RFLSQ 281_ VLGRV 286_ LQLLP 291_ PGQVQ 296_ VHKMK 301_ AVYLA 306_ LNQCS 311_ VSTTH 316_ KCLIA 321_ EAWCS 326_ VRDLP 331_ ALQEA 336_ LRDSS 341_ MEEGV 346_ SAVAH 351_ RIPCR 356_ DMPPT 361_ LIRTN 366_ RFTAS 371_ FQGIV 376_ DAYGV 381_ GRYQE 386_ VNPAP 391_ YTIIT 396_ FPFLF 401_ AVMFG 406_ DVGHG 411_ LLMFL 416_ FALAM 421_ VLAEN 426_ RPAVK 431_ AAQNE 436_ IWQTF 441_ FRGRY 446_ LLLLM 451_ GLFSI 456_ YTGFI 461_ YNECF 466_ SRATS 471_ IFPSG 476_ WSVAA 481_ MANQS 486_ GWSDA 491_ FLAQH 496_ TMLTL 501_ DPNVT 506_ GVFLG 511_ PYPFG 516_ IDPIW 521_ SLAAN 526_ HLSFL 531_ NSFKM 536_ KMSVI 541_ LGVVH 546_ MAFGV 551_ VLGVF 556_ NHVHF 561_ GQRHR 566_ LLLET 571_ LPELT 576_ FLLGL 581_ FGYLV 586_ FLVIY 591_ KWLCV 596_ WAARA 601_ ASAPS 606_ ILIHF 611_ INMFL 616_ FSHSP 621_ SNRLL 626_ YPRQE 631_ VVQAT 636_ LVVLA 641_ LAMVP 646_ ILLLG 651_ TPLHL 656_ LHRHR 661_ RRLRR 666_ RPADR 671_ QEENK 676_ AGLLD 681_ LPDAS 686_ VNGWS 691_ SDEEK 696_ AGGLD 701_ DEEEA 706_ ELVPS 711_ EVLMH 716_ QAIHT 721_ IEFCL 726_ GCVSN 731_ TASYL 736_ RLWAL 741_ SLAHA 746_ QLSEV 751_ LWAMV 756_ MRIGL 761_ GLGRE 766_ VGVAA 771_ VVLVP 776_ IFAAF 781_ AVMTV 786_ AILLV 791_ MEGLS 796_ AFLHA 801_ LRLHW 806_ VEFQN 811_ KFYSG 816_ TGYKL 821_SPFTF
1: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Seems to be directly involved in T-cell activation (PubMed:10329006)