Oligodendrocyte transcription factor 2 (Oligo2) (Class B basic helix-loop-helix protein 1) (bHLHb1) (Class E basic helix-loop-helix protein 19) (bHLHe19) (Protein kinase C-binding protein 2) (Protein kinase C-binding protein RACK17)
1_MDSDA 6_ SLVSS 11_ RPSSP 16_ EPDDL 21_ FLPAR 26_ SKGSS 31_ GSAFT 36_ GGTVS 41_ SSTPS 46_ DCPPE 51_ LSAEL 56_ RGAMG 61_ SAGAH 66_ PGDKL 71_ GGSGF 76_ KSSSS 81_ STSSS 86_ TSSAA 91_ ASSTK 96_ KDKKQ 101_ MTEPE 106_ LQQLR 111_ LKINS 116_ RERKR 121_ MHDLN 126_ IAMDG 131_ LREVM 136_ PYAHG 141_ PSVRK 146_ LSKIA 151_ TLLLA 156_ RNYIL 161_ MLTNS 166_ LEEMK 171_ RLVSE 176_ IYGGH 181_ HAGFH 186_ PSACG 191_ GLAHS 196_ APLPA 201_ ATAHP 206_ AAAAH 211_ AAHHP 216_ AVHHP 221_ ILPPA 226_ AAAAA 231_ AAAAA 236_ AAVSS 241_ ASLPG 246_ SGLPS 251_ VGSIR 256_ PPHGL 261_ LKSPS 266_ AAAAA 271_ PLGGG 276_ GGGSG 281_ ASGGF 286_ QHWGG 291_ MPCPC 296_ SMCQV 301_ PPPHH 306_ HVSAM 311_ GAGSL 316_PRLTS
1: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development