Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
1_MATTA 6_ TCTRF 11_ TDDYQ 16_ LFEEL 21_ GKGAF 26_ SVVRR 31_ CVKKT 36_ STQEY 41_ AAKII 46_ NTKKL 51_ SARDH 56_ QKLER 61_ EARIC 66_ RLLKH 71_ PNIVR 76_ LHDSI 81_ SEEGF 86_ HYLVF 91_ DLVTG 96_ GELFE 101_ DIVAR 106_ EYYSE 111_ ADASH 116_ CIHQI 121_ LESVN 126_ HIHQH 131_ DIVHR 136_ DLKPE 141_ NLLLA 146_ SKCKG 151_ AAVKL 156_ ADFGL 161_ AIEVQ 166_ GEQQA 171_ WFGFA 176_ GTPGY 181_ LSPEV 186_ LRKDP 191_ YGKPV 196_ DIWAC 201_ GVILY 206_ ILLVG 211_ YPPFW 216_ DEDQH 221_ KLYQQ 226_ IKAGA 231_ YDFPS 236_ PEWDT 241_ VTPEA 246_ KNLIN 251_ QMLTI 256_ NPAKR 261_ ITADQ 266_ ALKHP 271_ WVCQR 276_ STVAS 281_ MMHRQ 286_ ETVEC 291_ LRKFN 296_ ARRKL 301_ KGAIL 306_ TTMLV 311_ SRNFS 316_ AAKSL 321_ LNKKS 326_ DGGVK 331_ KRKSS 336_ SSVHL 341_ MPQSN 346_ NKNSL 351_ VSPAQ 356_ EPAPL 361_ QTAME 366_ PQTTV 371_ VHNAT 376_ DGIKG 381_ STESC 386_ NTTTE 391_ DEDLK 396_ GRVPE 401_ GRSSR 406_ DRTAP 411_ SAGMQ 416_ PQPSL 421_ CSSAM 426_ RKQEI 431_ IKITE 436_ QLIEA 441_ INNGD 446_ FEAYT 451_ KICDP 456_ GLTSF 461_ EPEAL 466_ GNLVE 471_ GMDFH 476_ KFYFE 481_ NLLSK 486_ NSKPI 491_ HTTIL 496_ NPHVH 501_ VIGED 506_ AACIA 511_ YIRLT 516_ QYIDG 521_ QGRPR 526_ TSQSE 531_ ETRVW 536_ HRRDG 541_ KWLNV 546_ HYHCS 551_GAPAA
1: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity (PubMed:16690701). In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin (PubMed:16690701). In the central nervous system, it is involved in the regulation of neurite formation and arborization (PubMed:30184290). It may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity)