Solute carrier family 12 member 1 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (Kidney-specific Na-K-Cl symporter)
1_MSLNN 6_ SSNVF 11_ LDSVP 16_ SNTNR 21_ FQVSV 26_ INENH 31_ ESSAA 36_ ADDNT 41_ DPPHY 46_ EETSF 51_ GDEAQ 56_ KRLRI 61_ SFRPG 66_ NQECY 71_ DNFLQ 76_ SGETA 81_ KTDAS 86_ FHAYD 91_ SHTNT 96_ YYLQT 101_ FGHNT 106_ MDAVP 111_ KIEYY 116_ RNTGS 121_ ISGPK 126_ VNRPS 131_ LLEIH 136_ EQLAK 141_ NVAVT 146_ PSSAD 151_ RVANG 156_ DGIPG 161_ DEQAE 166_ NKEDD 171_ QAGVV 176_ KFGWV 181_ KGVLV 186_ RCMLN 191_ IWGVM 196_ LFIRL 201_ SWIVG 206_ EAGIG 211_ LGVLI 216_ ILLST 221_ MVTSI 226_ TGLST 231_ SAIAT 236_ NGFVR 241_ GGGAY 246_ YLISR 251_ SLGPE 256_ FGGSI 261_ GLIFA 266_ FANAV 271_ AVAMY 276_ VVGFA 281_ ETVVD 286_ LLKES 291_ DSMMV 296_ DPTND 301_ IRIIG 306_ SITVV 311_ ILLGI 316_ SVAGM 321_ EWEAK 326_ AQVIL 331_ LVILL 336_ IAIAN 341_ FFIGT 346_ VIPSN 351_ NEKKS 356_ RGFFN 361_ YQASI 366_ FAENF 371_ GPRFT 376_ KGEGF 381_ FSVFA 386_ IFFPA 391_ ATGIL 396_ AGANI 401_ SGDLE 406_ DPQDA 411_ IPRGT 416_ MLAIF 421_ ITTVA 426_ YLGVA 431_ ICVGA 436_ CVVRD 441_ ATGNM 446_ NDTII 451_ SGMNC 456_ NGSAA 461_ CGLGY 466_ DFSRC 471_ RHEPC 476_ QYGLM 481_ NNFQV 486_ MSMVS 491_ GFGPL 496_ ITAGI 501_ FSATL 506_ SSALA 511_ SLVSA 516_ PKVFQ 521_ ALCKD 526_ NIYKA 531_ LQFFA 536_ KGYGK 541_ NNEPL 546_ RGYIL 551_ TFLIA 556_ MAFIL 561_ IAELN 566_ TIAPI 571_ ISNFF 576_ LASYA 581_ LINFS 586_ CFHAS 591_ YAKSP 596_ GWRPA 601_ YGIYN 606_ MWVSL 611_ FGAVL 616_ CCAVM 621_ FVINW 626_ WAAVI 631_ TYVIE 636_ FFLYV 641_ YVTCK 646_ KPDVN 651_ WGSST 656_ QALSY 661_ VSALD 666_ NALEL 671_ TTVED 676_ HVKNF 681_ RPQCI 686_ VLTGG 691_ PMTRP 696_ ALLDI 701_ THAFT 706_ KNSGL 711_ CICCE 716_ VFVGP 721_ RKLCV 726_ KEMNS 731_ GMAKK 736_ QAWLI 741_ KNKIK 746_ AFYAA 751_ VAADC 756_ FRDGV 761_ RSLLQ 766_ ASGLG 771_ RMKPN 776_ TLVIG 781_ YKKNW 786_ RKAPL 791_ TEIEN 796_ YVGII 801_ HDAFD 806_ FEIGV 811_ VIVRI 816_ SQGFD 821_ ISQVL 826_ QVQEE 831_ LERLE 836_ QERLA 841_ LEATI 846_ KDNEC 851_ EEESG 856_ GIRGL 861_ FKKAG 866_ KLNIT 871_ KTTPK 876_ KDGSI 881_ NTSQS 886_ MHVGE 891_ FNQKL 896_ VEAST 901_ QFKKK 906_ QEKGT 911_ IDVWW 916_ LFDDG 921_ GLTLL 926_ IPYIL 931_ TLRKK 936_ WKDCK 941_ LRIYV 946_ GGKIN 951_ RIEEE 956_ KIVMA 961_ SLLSK 966_ FRIKF 971_ ADIHI 976_ IGDIN 981_ IRPNK 986_ ESWKV 991_ FEEMI 996_ EPYRL 1001_ HESCK 1006_ DLTTA 1011_ EKLKR 1016_ ETPWK 1021_ ITDAE 1026_ LEAVK 1031_ EKSYR 1036_ QVRLN 1041_ ELLQE 1046_ HSRAA 1051_ NLIVL 1056_ SLPVA 1061_ RKGSI 1066_ SDLLY 1071_ MAWLE 1076_ ILTKN 1081_ LPPVL 1086_ LVRGN 1091_HKNVL
1: Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation (PubMed:21321328). Electrically silent transporter system (By similarity)