GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)
1_MGEPQ 6_ GSMRI 11_ LVTGG 16_ SGLVG 21_ KAIQK 26_ VVADG 31_ AGLPG 36_ EDWVF 41_ VSSKD 46_ ADLTD 51_ TAQTR 56_ ALFEK 61_ VQPTH 66_ VIHLA 71_ AMVGG 76_ LFRNI 81_ KYNLD 86_ FWRKN 91_ VHMND 96_ NVLHS 101_ AFEVG 106_ ARKVV 111_ SCLST 116_ CIFPD 121_ KTTYP 126_ IDETM 131_ IHNGP 136_ PHNSN 141_ FGYSY 146_ AKRMI 151_ DVQNR 156_ AYFQQ 161_ YGCTF 166_ TAVIP 171_ TNVFG 176_ PHDNF 181_ NIEDG 186_ HVLPG 191_ LIHKV 196_ HLAKS 201_ SGSAL 206_ TVWGT 211_ GNPRR 216_ QFIYS 221_ LDLAQ 226_ LFIWV 231_ LREYN 236_ EVEPI 241_ ILSVG 246_ EEDEV 251_ SIKEA 256_ AEAVV 261_ EAMDF 266_ HGEVT 271_ FDTTK 276_ SDGQF 281_ KKTAS 286_ NSKLR 291_ TYLPD 296_ FRFTP 301_ FKQAV 306_ KETCA 311_ WFTDN 316_YEQAR
1: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction