Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)
1_MPSSS 6_ DTALG 11_ GGGGL 16_ SWAEK 21_ KLEER 26_ RKRRR 31_ FLSPQ 36_ QPPLL 41_ LPLLQ 46_ PQLLQ 51_ PPPPP 56_ PPLLF 61_ LAAPG 66_ TAAAA 71_ AAAAA 76_ ASSSC 81_ FSPGP 86_ PLEVK 91_ RLARG 96_ KRRAG 101_ GRQKR 106_ RRGPR 111_ AGQEA 116_ EKRRV 121_ FSLPQ 126_ PQQDG 131_ GGGAS 136_ SGGGV 141_ TPLVE 146_ YEDVS 151_ SQSEQ 156_ GLLLG 161_ GASAA 166_ TAATA 171_ AGGTG 176_ GSGGS 181_ PASSS 186_ GTQRR 191_ GEGSE 196_ RRPRR 201_ DRRSS 206_ SGRSK 211_ ERHRE 216_ HRRRD 221_ GQRGG 226_ SEASK 231_ SRSRH 236_ SHSGE 241_ ERAEV 246_ AKSGS 251_ SSSSG 256_ GRRKS 261_ ASATS 266_ SSSSS 271_ RKDRD 276_ SKAHR 281_ SRTKS 286_ SKEPP 291_ SAYKE 296_ PPKAY 301_ REDKT 306_ EPKAY 311_ RRRRS 316_ LSPLG 321_ GRDDS 326_ PVSHR 331_ ASQSL 336_ RSRKS 341_ PSPAG 346_ GGSSP 351_ YSRRL 356_ PRSPS 361_ PYSRR 366_ RSPSY 371_ SRHSS 376_ YERGG 381_ DVSPS 386_ PYSSS 391_ SWRRS 396_ RSPYS 401_ PVLRR 406_ SGKSR 411_ SRSPY 416_ SSRHS 421_ RSRSR 426_ HRLSR 431_ SRSRH 436_ SSISP 441_ STLTL 446_ KSSLA 451_ AELNK 456_ NKKAR 461_ AAEAA 466_ RAAEA 471_ AKAAE 476_ ATKAA 481_ EAAAK 486_ AAKAS 491_ NTSTP 496_ TKGNT 501_ ETSAS 506_ ASQTN 511_ HVKDV 516_ KKIKI 521_ EHAPS 526_ PSSGG 531_ TLKND 536_ KAKTK 541_ PPLQV 546_ TKVEN 551_ NLIVD 556_ KATKK 561_ AVIVG 566_ KESKS 571_ AATKE 576_ ESVSL 581_ KEKTK 586_ PLTPS 591_ IGAKE 596_ KEQHV 601_ ALVTS 606_ TLPPL 611_ PLPPM 616_ LPEDK 621_ EADSL 626_ RGNIS 631_ VKAVK 636_ KEVEK 641_ KLRCL 646_ LADLP 651_ LPPEL 656_ PGGDD 661_ LSKSP 666_ EEKKT 671_ ATQLH 676_ SKRRP 681_ KICGP 686_ RYGET 691_ KEKDI 696_ DWGKR 701_ CVDKF 706_ DIIGI 711_ IGEGT 716_ YGQVY 721_ KARDK 726_ DTGEM 731_ VALKK 736_ VRLDN 741_ EKEGF 746_ PITAI 751_ REIKI 756_ LRQLT 761_ HQSII 766_ NMKEI 771_ VTDKE 776_ DALDF 781_ KKDKG 786_ AFYLV 791_ FEYMD 796_ HDLMG 801_ LLESG 806_ LVHFN 811_ ENHIK 816_ SFMRQ 821_ LMEGL 826_ DYCHK 831_ KNFLH 836_ RDIKC 841_ SNILL 846_ NNRGQ 851_ IKLAD 856_ FGLAR 861_ LYSSE 866_ ESRPY 871_ TNKVI 876_ TLWYR 881_ PPELL 886_ LGEER 891_ YTPAI 896_ DVWSC 901_ GCILG 906_ ELFTK 911_ KPIFQ 916_ ANQEL 921_ AQLEL 926_ ISRIC 931_ GSPCP 936_ AVWPD 941_ VIKLP 946_ YFNTM 951_ KPKKQ 956_ YRRKL 961_ REEFV 966_ FIPAA 971_ ALDLF 976_ DYMLA 981_ LDPSK 986_ RCTAE 991_ QALQC 996_ EFLRD 1001_ VEPSK 1006_ MPPPD 1011_ LPLWQ 1016_ DCHEL 1021_ WSKKR 1026_ RRQKQ 1031_ MGMTD 1036_ DVSTI 1041_ KAPRK 1046_ DLSLG 1051_ LDDSR 1056_ TNTPQ 1061_ GVLPS 1066_ SQLKS 1071_ QGSSN 1076_ VAPVK 1081_ TGPGQ 1086_ HLNHS 1091_ ELAIL 1096_ LNLLQ 1101_ SKTSV 1106_ NMADF 1111_ VQVLN 1116_ IKVNS 1121_ ETQQQ 1126_ LNKIN 1131_ LPAGI 1136_ LATGE 1141_ KQTDP 1146_ STPQQ 1151_ ESSKP 1156_ LGGIQ 1161_ PSSQT 1166_ IQPKV 1171_ ETDAA 1176_ QAAVQ 1181_ SAFAV 1186_ LLTQL 1191_ IKAQQ 1196_ SKQKD 1201_ VLLEE 1206_ RENGS 1211_ GHEAS 1216_ LQLRP 1221_ PPEPS 1226_ TPVSG 1231_ QDDLI 1236_ QHQDM 1241_ RILEL 1246_ TPEPD 1251_ RPRIL 1256_ PPDQR 1261_ PPEPP 1266_ EPPPV 1271_ TEEDL 1276_ DYRTE 1281_ NQHVP 1286_ TTSSS 1291_ LTDPH 1296_ AGVKA 1301_ ALLQL 1306_ LAQHQ 1311_ PQDDP 1316_ KREGG 1321_ IDYQA 1326_ GDTYV 1331_ STSDY 1336_ KDNFG 1341_ SSSFS 1346_ SAPYV 1351_ SNDGL 1356_ GSSSA 1361_ PPLER 1366_ RSFIG 1371_ NSDIQ 1376_ SLDNY 1381_ STASS 1386_ HSGGP 1391_ PQPSA 1396_ FSESF 1401_ PSSVA 1406_ GYGDI 1411_ YLNAG 1416_ PMLFS 1421_ GDKDH 1426_ RFEYS 1431_ HGPIA 1436_ VLANS 1441_ SDPST 1446_ GPEST 1451_ HPLPA 1456_ KMHNY 1461_ NYGGN 1466_ LQENP 1471_ SGPSL 1476_ MHGQT 1481_ WTSPA 1486_ QGPGY 1491_ SQGYR 1496_ GHIST 1501_ STGRG 1506_RGRGL
1: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef