Transcription factor Dp-2 (E2F dimerization partner 2)
1_MTAKN 6_ VGLTS 11_ TNAEV 16_ RGFID 21_ QNLSP 26_ TKGNI 31_ SFVAF 36_ PVSNT 41_ NSPTK 46_ ILPKT 51_ LGPIN 56_ VNVGP 61_ QMIIS 66_ TPQRL 71_ TSSGS 76_ VLIGS 81_ PYTPA 86_ PAMVT 91_ QTHIA 96_ EATGW 101_ VPGDR 106_ KRARK 111_ FIDSD 116_ FSESK 121_ RSKKG 126_ DKNGK 131_ GLRHF 136_ SMKVC 141_ EKVQR 146_ KGTTS 151_ YNEVA 156_ DELVS 161_ EFTNS 166_ NNHLA 171_ ADSAY 176_ DQKNI 181_ RRRVY 186_ DALNV 191_ LMAMN 196_ IISKE 201_ KKEIK 206_ WIGLP 211_ TNSAQ 216_ ECQNL 221_ EIEKQ 226_ RRIER 231_ IKQKR 236_ AQLQE 241_ LLLQQ 246_ IAFKN 251_ LVQRN 256_ RQNEQ 261_ QNQGP 266_ PALNS 271_ TIQLP 276_ FIIIN 281_ TSRKT 286_ VIDCS 291_ ISSDK 296_ FEYLF 301_ NFDNT 306_ FEIHD 311_ DIEVL 316_ KRMGM 321_ SFGLE 326_ SGKCS 331_ LEDLK 336_ LAKSL 341_ VPKAL 346_ EGYIT 351_ DISTG 356_ PSWLN 361_ QGLLL 366_ NSTQS 371_ VSNLD 376_ LTTGA 381_ TLPQS 386_ SVNQG 391_ LCLDA 396_ EVALA 401_ TGQFL 406_ APNSH 411_ QSSSA 416_ ASHCS 421_ ESRGE 426_ TPCSF 431_ NDEDE 436_ EDDEE 441_DSSSP
1: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812)