Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
1_MTERF 6_ DCHHC 11_ NESLF 16_ GKKYI 21_ LREES 26_ PYCVV 31_ CFETL 36_ FANTC 41_ EECGK 46_ PIGCD 51_ CKDLS 56_ YKDRH 61_ WHEAC 66_ FHCSQ 71_ CRNSL 76_ VDKPF 81_ AAKED 86_ QLLCT 91_ DCYSN 96_ EYSSK 101_ CQECK 106_ KTIMP 111_ GTRKM 116_ EYKGS 121_ SWHET 126_ CFICH 131_ RCQQP 136_ IGTKS 141_ FIPKD 146_ NQNFC 151_ VPCYE 156_ KQHAM 161_ QCVQC 166_ KKPIT 171_ TGGVT 176_ YREQP 181_ WHKEC 186_ FVCTA 191_ CRKQL 196_ SGQRF 201_ TARDD 206_ FAYCL 211_ NCFCD 216_ LYAKK 221_ CAGCT 226_ NPISG 231_ LGGTK 236_ YISFE 241_ ERQWH 246_ NDCFN 251_ CKKCS 256_ LSLVG 261_ RGFLT 266_ ERDDI 271_LCPDC
1: May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008)