Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)
1_MTEKM 6_ SSFLY 11_ IGDIV 16_ SLYAE 21_ GSVNG 26_ FISTL 31_ GLVDD 36_ RCVVH 41_ PEAGD 46_ LANPP 51_ KKFRD 56_ CLFKV 61_ CPMNR 66_ YSAQK 71_ QYWKA 76_ KQAKQ 81_ GNHTE 86_ AALLK 91_ KLQHA 96_ AELEQ 101_ KQNES 106_ ENKKL 111_ LGEIV 116_ KYSNV 121_ IQLLH 126_ IKSNK 131_ YLTVN 136_ KRLPA 141_ LLEKN 146_ AMRVS 151_ LDAAG 156_ NEGSW 161_ FYIHP 166_ FWKLR 171_ SEGDN 176_ IVVGD 181_ KVVLM 186_ PVNAG 191_ QPLHA 196_ SNIEL 201_ LDNPG 206_ CKEVN 211_ AVNCN 216_ TSWKI 221_ TLFMK 226_ YSSYR 231_ EDVLK 236_ GGDVV 241_ RLFHA 246_ EQEKF 251_ LTCDE 256_ YEKKQ 261_ HIFLR 266_ TTLRQ 271_ SATSA 276_ TSSKA 281_ LWEIE 286_ VVHHD 291_ PCRGG 296_ AGQWN 301_ SLFRF 306_ KHLAT 311_ GNYLA 316_ AELNP 321_ DYRDA 326_ QNEGK 331_ NVRDG 336_ VPPTS 341_ KKKRQ 346_ AGEKI 351_ MYTLV 356_ SVPHG 361_ NDIAS 366_ LFELD 371_ ATTLQ 376_ RADCL 381_ VPRNS 386_ YVRLR 391_ HLCTN 396_ TWVTS 401_ TSIPI 406_ DTDEE 411_ RPVML 416_ KIGTC 421_ QTKED 426_ KEAFA 431_ IVSVP 436_ LSEVR 441_ DLDFA 446_ NDANK 451_ VLATT 456_ VKKLE 461_ NGTIT 466_ QNERR 471_ FVTKL 476_ LEDLI 481_ FFVAD 486_ VPNNG 491_ QEVLD 496_ VVITK 501_ PNRER 506_ QKLMR 511_ EQNIL 516_ AQVFG 521_ ILKAP 526_ FKEKA 531_ GEGSM 536_ LRLED 541_ LGDQR 546_ YAPYK 551_ YMLRL 556_ CYRVL 561_ RHSQQ 566_ DYRKN 571_ QEYIA 576_ KNFCV 581_ MQSQI 586_ GYDIL 591_ AEDTI 596_ TALLH 601_ NNRKL 606_ LEKHI 611_ TAKEI 616_ ETFVS 621_ LLRRN 626_ REPRF 631_ LDYLS 636_ DLCVS 641_ NTTAI 646_ PVTQE 651_ LICKF 656_ MLSPG 661_ NADIL 666_ IQTKV 671_ VSMQA 676_ DNPME 681_ SSILS 686_ DDIDD 691_ EEVWL 696_ YWIDS 701_ NKEPH 706_ GKAIR 711_ HLAQE 716_ AKEGT 721_ KADLE 726_ VLTYY 731_ RYQLN 736_ LFARM 741_ CLDRQ 746_ YLAIN 751_ QISTQ 756_ LSVDL 761_ ILRCV 766_ SDESL 771_ PFDLR 776_ ASFCR 781_ LMLHM 786_ HVDRD 791_ PQESV 796_ VPVRY 801_ ARLWT 806_ EIPTK 811_ ITIHE 816_ YDSIT 821_ DSSRN 826_ DMKRK 831_ FALTM 836_ EFVEE 841_ YLKEV 846_ VNQPF 851_ PFGDK 856_ EKNKL 861_ TFEVV 866_ HLARN 871_ LIYFG 876_ FYSFS 881_ ELLRL 886_ TRTLL 891_ AILDI 896_ VQAPM 901_ SSYFE 906_ RLSKF 911_ QDGGN 916_ NVMRT 921_ IHGVG 926_ EMMTQ 931_ MVLSR 936_ GSIFP 941_ MSVPD 946_ VPPSI 951_ HPSKQ 956_ GSPTE 961_ HEDVT 966_ VMDTK 971_ LKIIE 976_ ILQFI 981_ LSVRL 986_ DYRIS 991_ YMLSI 996_ YKKEF 1001_ GEDND 1006_ NAETS 1011_ ASGSP 1016_ DTLLP 1021_ SAIVP 1026_ DIDEI 1031_ AAQAE 1036_ TMFAG 1041_ RKEKN 1046_ PVQLD 1051_ DEGGR 1056_ TFLRV 1061_ LIHLI 1066_ MHDYP 1071_ PLLSG 1076_ ALQLL 1081_ FKHFS 1086_ QRAEV 1091_ LQAFK 1096_ QVQLL 1101_ VSNQD 1106_ VDNYK 1111_ QIKAD 1116_ LDQLR 1121_ LTVEK 1126_ SELWV 1131_ EKSSN 1136_ YENGE 1141_ IGESQ 1146_ VKGGE 1151_ EPIEE 1156_ SNILS 1161_ PVQDG 1166_ TKKPQ 1171_ IDSNK 1176_ SNNYR 1181_ IVKEI 1186_ LIRLS 1191_ KLCVQ 1196_ NKKCR 1201_ NQHQR 1206_ LLKNM 1211_ GAHSV 1216_ VLDLL 1221_ QIPYE 1226_ KNDEK 1231_ MNEVM 1236_ NLAHT 1241_ FLQNF 1246_ CRGNP 1251_ QNQVL 1256_ LHKHL 1261_ NLFLT 1266_ PGLLE 1271_ AETMR 1276_ HIFMN 1281_ NYHLC 1286_ NEISE 1291_ RVVQH 1296_ FVHCI 1301_ ETHGR 1306_ HVEYL 1311_ RFLQT 1316_ IVKAD 1321_ GKYVK 1326_ KCQDM 1331_ VMTEL 1336_ INGGE 1341_ DVLIF 1346_ YNDRA 1351_ SFPIL 1356_ LHMMC 1361_ SERDR 1366_ GDESG 1371_ PLAYH 1376_ ITLVE 1381_ LLAAC 1386_ TEGKN 1391_ VYTEI 1396_ KCNSL 1401_ LPLDD 1406_ IVRVV 1411_ THDDC 1416_ IPEVK 1421_ IAYVN 1426_ FVNHC 1431_ YVDTE 1436_ VEMKE 1441_ IYTSN 1446_ HIWKL 1451_ FENFL 1456_ VDMAR 1461_ VCNTT 1466_ TDRKH 1471_ ADIFL 1476_ EKCVT 1481_ ESIMN 1486_ IVSGF 1491_ FNSPF 1496_ SDNST 1501_ SLQTH 1506_ QPVFI 1511_ QLLQS 1516_ AFRIY 1521_ NCTWP 1526_ NPAQK 1531_ ASVES 1536_ CIRTL 1541_ AEVAK 1546_ NRGIA 1551_ IPVDL 1556_ DSQVN 1561_ TLFMK 1566_ SHSNM 1571_ VQRAA 1576_ MGWRL 1581_ SARSG 1586_ PRFKE 1591_ ALGGP 1596_ AWDYR 1601_ NIIEK 1606_ LQDVV 1611_ ASLEH 1616_ QFSPM 1621_ MQAEF 1626_ SVLVD 1631_ VLYSP 1636_ ELLFP 1641_ EGSDA 1646_ RIRCG 1651_ AFMSK 1656_ LINHT 1661_ KKLME 1666_ KEEKL 1671_ CIKIL 1676_ QTLRE 1681_ MLEKK 1686_ DSFVE 1691_ EGNTL 1696_ RKILL 1701_ NRYFK 1706_ GDYSI 1711_ GVNGH 1716_ LSGAY 1721_ SKTAQ 1726_ VGGSF 1731_ SGQDS 1736_ DKMGI 1741_ SMSDI 1746_ QCLLD 1751_ KEGAS 1756_ ELVID 1761_ VIVNT 1766_ KNDRI 1771_ FSEGI 1776_ FLGIA 1781_ LLEGG 1786_ NTQTQ 1791_ YSFYQ 1796_ QLHEQ 1801_ KKSEK 1806_ FFKVL 1811_ YDRMK 1816_ AAQKE 1821_ IRSTV 1826_ TVNTI 1831_ DLGNK 1836_ KRDDD 1841_ NELMT 1846_ SGPRM 1851_ RVRDS 1856_ TLHLK 1861_ EGMKG 1866_ QLTEA 1871_ SSATS 1876_ KAYCV 1881_ YRREM 1886_ DPEID 1891_ IMCTG 1896_ PEAGN 1901_ TEEKS 1906_ AEEVT 1911_ MSPAI 1916_ AIMQP 1921_ ILRFL 1926_ QLLCE 1931_ NHNRE 1936_ LQNFL 1941_ RNQNN 1946_ KTNYN 1951_ LVCET 1956_ LQFLD 1961_ CICGS 1966_ TTGGL 1971_ GLLGL 1976_ YINEK 1981_ NVALV 1986_ NQNLE 1991_ SLTEY 1996_ CQGPC 2001_ HENQT 2006_ CIATH 2011_ ESNGI 2016_ DIIIA 2021_ LILND 2026_ INPLG 2031_ KYRMD 2036_ LVLQL 2041_ KNNAS 2046_ KLLLA 2051_ IMESR 2056_ HDSEN 2061_ AERIL 2066_ FNMRP 2071_ RELVD 2076_ VMKNA 2081_ YNQGL 2086_ ECDHG 2091_ DDEGG 2096_ DDGVS 2101_ PKDVG 2106_ HNIYI 2111_ LAHQL 2116_ ARHNK 2121_ LLQQM 2126_ LKPGS 2131_ DPDEG 2136_ DEALK 2141_ YYANH 2146_ TAQIE 2151_ IVRHD 2156_ RTMEQ 2161_ IVFPV 2166_ PNICE 2171_ YLTRE 2176_ SKCRV 2181_ FNTTE 2186_ RDEQG 2191_ SKVND 2196_ FFQQT 2201_ EDLYN 2206_ EMKWQ 2211_ KKIRN 2216_ NPALF 2221_ WFSRH 2226_ ISLWG 2231_ SISFN 2236_ LAVFI 2241_ NLAVA 2246_ LFYPF 2251_ GDDGD 2256_ EGTLS 2261_ PLFSV 2266_ LLWIA 2271_ VAICT 2276_ SMLFF 2281_ FSKPV 2286_ GIRPF 2291_ LVSIM 2296_ LRSIY 2301_ TIGLG 2306_ PTLIL 2311_ LGAAN 2316_ LCNKI 2321_ VFLVS 2326_ FVGNR 2331_ GTFTR 2336_ GYRAV 2341_ ILDMA 2346_ FLYHV 2351_ AYVLV 2356_ CMLGL 2361_ FVHEF 2366_ FYSFL 2371_ LFDLV 2376_ YREET 2381_ LLNVI 2386_ KSVTR 2391_ NGRSI 2396_ ILTAV 2401_ LALIL 2406_ VYLFS 2411_ IIGFL 2416_ FLKDD 2421_ FTMEV 2426_ DRLKN 2431_ RTPVT 2436_ GSHQV 2441_ PTMTL 2446_ TTMME 2451_ ACAKE 2456_ NCSPT 2461_ IPASN 2466_ TADEE 2471_ YEDGI 2476_ ERTCD 2481_ TLLMC 2486_ IVTVL 2491_ NQGLR 2496_ NGGGV 2501_ GDVLR 2506_ RPSKD 2511_ EPLFA 2516_ ARVVY 2521_ DLLFY 2526_ FIVII 2531_ IVLNL 2536_ IFGVI 2541_ IDTFA 2546_ DLRSE 2551_ KQKKE 2556_ EILKT 2561_ TCFIC 2566_ GLERD 2571_ KFDNK 2576_ TVSFE 2581_ EHIKS 2586_ EHNMW 2591_ HYLYF 2596_ IVLVK 2601_ VKDPT 2606_ EYTGP 2611_ ESYVA 2616_ QMIVE 2621_ KNLDW 2626_ FPRMR 2631_ AMSLV 2636_ SNEGD 2641_ SEQNE 2646_ IRSLQ 2651_ EKLES 2656_ TMSLV 2661_ KQLSG 2666_ QLAEL 2671_ KEQMT 2676_ EQRKN 2681_ KQRLG 2686_ FLGSN 2691_ TPHVN 2696_HHMPP
1: Inositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm. Exists in two states; a long-lived closed state where the channel is essentially 'parked' with only very rare visits to an open state and that ligands facilitate the transition from the 'parked' state into a 'drive' mode represented by periods of bursting activity (By similarity)