ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21)
1_MVTQI 6_ LGAME 11_ SQVGG 16_ GPAGP 21_ ALPNG 26_ PLLGT 31_ NGATD 36_ DSKTN 41_ LIVNY 46_ LPQNM 51_ TQDEF 56_ KSLFG 61_ SIGDI 66_ ESCKL 71_ VRDKI 76_ TGQSL 81_ GYGFV 86_ NYSDP 91_ NDADK 96_ AINTL 101_ NGLKL 106_ QTKTI 111_ KVSYA 116_ RPSSA 121_ SIRDA 126_ NLYVS 131_ GLPKT 136_ MSQKE 141_ MEQLF 146_ SQYGR 151_ IITSR 156_ ILVDQ 161_ VTGVS 166_ RGVGF 171_ IRFDK 176_ RIEAE 181_ EAIKG 186_ LNGQK 191_ PLGAA 196_ EPITV 201_ KFANN 206_ PSQKT 211_ GQALL 216_ THLYQ 221_ SSARR 226_ YAGPL 231_ HHQTQ 236_ RFRLD 241_ NLLNM 246_ AYGVK 251_ SPLSL 256_ IARFS 261_ PIAID 266_ GMSGL 271_ AGVGL 276_ SGGAA 281_ GAGWC 286_ IFVYN 291_ LSPEA 296_ DESVL 301_ WQLFG 306_ PFGAV 311_ TNVKV 316_ IRDFT 321_ TNKCK 326_ GFGFV 331_ TMTNY 336_ DEAAM 341_ AIASL 346_ NGYRL 351_ GERVL 356_ QVSFK 361_TSKQH
1: RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA (PubMed:10710437). May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance (By similarity). Plays a role in the stabilization of GAP43 mRNA and in spatial learning (By similarity)