Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4)
1_MELNS 6_ LLILL 11_ EAAEY 16_ LERRD 21_ REAEH 26_ GYASV 31_ LPFDG 36_ DFARE 41_ KTKAA 46_ GLVRK 51_ APNNR 56_ SSHNE 61_ LEKHR 66_ RAKLR 71_ LYLEQ 76_ LKQLV 81_ PLGPD 86_ STRHT 91_ TLSLL 96_ KRAKV 101_ HIKKL 106_ EEQDR 111_ RALSI 116_ KEQLQ 121_ QEHRF 126_ LKRRL 131_ EQLSV 136_ QSVER 141_ VRTDS 146_ TGSAV 151_ STDDS 156_ EQEVD 161_ IEGME 166_ FGPGE 171_ LDSVG 176_ SSSDA 181_ DDHYS 186_ LQSGT 191_ GGDSG 196_ FGPHC 201_RRLGR
1: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity)