Glycine N-methyltransferase (EC 2.1.1.20)
1_MVDSV 6_ YRTRS 11_ LGVAA 16_ EGLPD 21_ QYADG 26_ EAARV 31_ WQLYI 36_ GDTRS 41_ RTAEY 46_ KAWLL 51_ GLLRQ 56_ HGCQR 61_ VLDVA 66_ CGTGV 71_ DSIML 76_ VEEGF 81_ SVTSV 86_ DASDK 91_ MLKYA 96_ LKERW 101_ NRRHE 106_ PAFDK 111_ WVIEE 116_ ANWMT 121_ LDKDV 126_ PQSAE 131_ GGFDA 136_ VICLG 141_ NSFAH 146_ LPDCK 151_ GDQSE 156_ HRLAL 161_ KNIAS 166_ MVRAG 171_ GLLVI 176_ DHRNY 181_ DHILS 186_ TGCAP 191_ PGKNI 196_ YYKSD 201_ LTKDV 206_ TTSVL 211_ IVNNK 216_ AHMVT 221_ LDYTV 226_ QVPGA 231_ GQDGS 236_ PGLSK 241_ FRLSY 246_ YPHCL 251_ ASFTE 256_ LLQAA 261_ FGGKC 266_ QHSVL 271_ GDFKP 276_ YKPGQ 281_ TYIPC 286_YFIHV
1: Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine