Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)
1_MAGAW 6_ LRWGL 11_ LLWAG 16_ LLASS 21_ AHGRL 26_ RRITY 31_ VVHPG 36_ PGLAA 41_ GALPL 46_ SGPPR 51_ SRTFN 56_ VALNA 61_ RYSRS 66_ SAAAG 71_ APSRA 76_ SPGVP 81_ SERTR 86_ RTSKP 91_ GGAAL 96_ QGLRP 101_ PPPPP 106_ PEPAR 111_ PAVPG 116_ GQLHP 121_ NPGGH 126_ PAAAP 131_ FTKQG 136_ RQVVR 141_ SKVPQ 146_ ETQSG 151_ GGSRL 156_ QVHQK 161_ QQLQG 166_ VNVCG 171_ GRCCH 176_ GWSKA 181_ PGSQR 186_ CTKPS 191_ CVPPC 196_ QNGGM 201_ CLRPQ 206_ LCVCK 211_ PGTKG 216_ KACET 221_ IAAQD 226_ TSSPV 231_ FGGQS 236_ PGAAS 241_ SWGPP 246_ EQAAK 251_ HTSSK 256_ KADTL 261_ PRVSP 266_ VAQMT 271_ LTLKP 276_ KPSVG 281_ LPQQI 286_ HSQVT 291_ PLSSQ 296_ SVVIH 301_ HGQTQ 306_ EYVLK 311_ PKYFP 316_ AQKGI 321_ SGEQS 326_ TEGSF 331_ PLRYV 336_ QDQVA 341_ APFQL 346_ SNHTG 351_ RIKVV 356_ FTPSI 361_ CKVTC 366_ TKGSC 371_ QNSCE 376_ KGNTT 381_ TLISE 386_ NGHAA 391_ DTLTA 396_ TNFRV 401_ VICHL 406_ PCMNG 411_ GQCSS 416_ RDKCQ 421_ CPPNF 426_ TGKLC 431_ QIPVH 436_ GASVP 441_ KLYQH 446_ SQQPG 451_ KALGT 456_ HVIHS 461_ THTLP 466_ LTVTS 471_ QQGVK 476_ VKFPP 481_ NIVNI 486_ HVKHP 491_ PEASV 496_ QIHQV 501_ SRIDG 506_ PTGQK 511_ TKEAQ 516_ PGQSQ 521_ VSYQG 526_ LPVQK 531_ TQTIH 536_ STYSH 541_ QQVIP 546_ HVYPV 551_ AAKTQ 556_ LGRCF 561_ QETIG 566_ SQCGK 571_ ALPGL 576_ SKQED 581_ CCGTV 586_ GTSWG 591_ FNKCQ 596_ KCPKK 601_ PSYHG 606_ YNQMM 611_ ECLPG 616_ YKRVN 621_ NTFCQ 626_ DINEC 631_ QLQGV 636_ CPNGE 641_ CLNTM 646_ GSYRC 651_ TCKIG 656_ FGPDP 661_ TFSSC 666_ VPDPP 671_ VISEE 676_ KGPCY 681_ RLVSS 686_ GRQCM 691_ HPLSV 696_ HLTKQ 701_ LCCCS 706_ VGKAW 711_ GPHCE 716_ KCPLP 721_ GTAAF 726_ KEICP 731_ GGMGY 736_ TVSGV 741_ HRRRP 746_ IHHHV 751_ GKGPV 756_ FVKPK 761_ NTQPV 766_ AKSTH 771_ PPPLP 776_ AKEEP 781_ VEALT 786_ FSREH 791_ GPGVA 796_ EPEVA 801_ TAPPE 806_ KEIPS 811_ LDQEK 816_ TKLEP 821_ GQPQL 826_ SPGIS 831_ TIHLH 836_ PQFPV 841_ VIEKT 846_ SPPVP 851_ VEVAP 856_ EASTS 861_ SASQV 866_ IAPTQ 871_ VTEIN 876_ ECTVN 881_ PDICG 886_ AGHCI 891_ NLPVR 896_ YTCIC 901_ YEGYR 906_ FSEQQ 911_ RKCVD 916_ IDECT 921_ QVQHL 926_ CSQGR 931_ CENTE 936_ GSFLC 941_ ICPAG 946_ FMASE 951_ EGTNC 956_ IDVDE 961_ CLRPD 966_ VCGEG 971_ HCVNT 976_ VGAFR 981_ CEYCD 986_ SGYRM 991_ TQRGR 996_ CEDID 1001_ ECLNP 1006_ STCPD 1011_ EQCVN 1016_ SPGSY 1021_ QCVPC 1026_ TEGFR 1031_ GWNGQ 1036_ CLDVD 1041_ ECLEP 1046_ NVCAN 1051_ GDCSN 1056_ LEGSY 1061_ MCSCH 1066_ KGYTR 1071_ TPDHK 1076_ HCRDI 1081_ DECQQ 1086_ GNLCV 1091_ NGQCK 1096_ NTEGS 1101_ FRCTC 1106_ GQGYQ 1111_ LSAAK 1116_ DQCED 1121_ IDECQ 1126_ HRHLC 1131_ AHGQC 1136_ RNTEG 1141_ SFQCV 1146_ CDQGY 1151_ RASGL 1156_ GDHCE 1161_ DINEC 1166_ LEDKS 1171_ VCQRG 1176_ DCINT 1181_ AGSYD 1186_ CTCPD 1191_ GFQLD 1196_ DNKTC 1201_ QDINE 1206_ CEHPG 1211_ LCGPQ 1216_ GECLN 1221_ TEGSF 1226_ HCVCQ 1231_ QGFSI 1236_ SADGR 1241_ TCEDI 1246_ DECVN 1251_ NTVCD 1256_ SHGFC 1261_ DNTAG 1266_ SFRCL 1271_ CYQGF 1276_ QAPQD 1281_ GQGCV 1286_ DVNEC 1291_ ELLSG 1296_ VCGEA 1301_ FCENV 1306_ EGSFL 1311_ CVCAD 1316_ ENQEY 1321_ SPMTG 1326_ QCRSR 1331_ TSTDL 1336_ DVDVD 1341_ QPKEE 1346_ KKECY 1351_ YNLND 1356_ ASLCD 1361_ NVLAP 1366_ NVTKQ 1371_ ECCCT 1376_ SGVGW 1381_ GDNCE 1386_ IFPCP 1391_ VLGTA 1396_ EFTEM 1401_ CPKGK 1406_ GFVPA 1411_ GESSS 1416_ EAGGE 1421_ NYKDA 1426_ DECLL 1431_ FGQEI 1436_ CKNGF 1441_ CLNTR 1446_ PGYEC 1451_ YCKQG 1456_ TYYDP 1461_ VKLQC 1466_ FDMDE 1471_ CQDPS 1476_ SCIDG 1481_ QCVNT 1486_ EGSYN 1491_ CFCTH 1496_ PMVLD 1501_ ASEKR 1506_ CIRPA 1511_ ESNEQ 1516_ IEETD 1521_ VYQDL 1526_ CWEHL 1531_ SDEYV 1536_ CSRPL 1541_ VGKQT 1546_ TYTEC 1551_ CCLYG 1556_ EAWGM 1561_ QCALC 1566_ PLKDS 1571_ DDYAQ 1576_ LCNIP 1581_ VTGRR 1586_ QPYGR 1591_ DALVD 1596_ FSEQY 1601_ TPEAD 1606_ PYFIQ 1611_ DRFLN 1616_ SFEEL 1621_ QAEEC 1626_ GILNG 1631_ CENGR 1636_ CVRVQ 1641_ EGYTC 1646_ DCFDG 1651_ YHLDT 1656_ AKMTC 1661_ VDVNE 1666_ CDELN 1671_ NRMSL 1676_ CKNAK 1681_ CINTD 1686_ GSYKC 1691_ LCLPG 1696_ YVPSD 1701_ KPNYC 1706_ TPLNT 1711_ ALNLE 1716_KDSDL
1: Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:2022183, PubMed:8617200, PubMed:8939931). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:15184403, PubMed:8617200, PubMed:8939931). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (PubMed:22278742)